2,4,5-Trifluoro-3-methylbenzamide

Base Information

Chemical Name:2,4,5-Trifluoro-3-methylbenzamide
CAS No.:112822-84-1
Molecular Formula:C8H6F3NO
Molecular Weight:189.137
Hs Code.:
DSSTox Substance ID:DTXSID20555108
Wikidata:Q82436344

Synonyms:2,4,5-Trifluoro-3-methylbenzamide;112822-84-1;SCHEMBL4514123;DTXSID20555108;FAHOHDHMFSGTMT-UHFFFAOYSA-N

Suppliers and Price of 2,4,5-Trifluoro-3-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,4,5-Trifluoro-3-methylbenzamide

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:189.04014830
Heavy Atom Count:13
Complexity:212

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC(=C1F)F)C(=O)N)F

Technology Process of 2,4,5-Trifluoro-3-methylbenzamide

There total 6 articles about 2,4,5-Trifluoro-3-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 112822-85-2
3-methyl-2,4,5-trifluorobenzoic acid

: 112822-84-1
2,4,5-trifluoro-3-methyl-benzamide

Guidance literature:: 3-methyl-2,4,5-trifluorobenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1.5h;

With ammonia; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1002/jhet.5570420428

Reference yield: 79.0%

: 74-88-4
methyl iodide

: 98349-23-6
2,4,5-trifluoro-benzamide

: 112822-84-1
2,4,5-trifluoro-3-methyl-benzamide

Guidance literature:: 2,4,5-trifluoro-benzamide; With lithium hexamethyldisilazane; In dichloromethane; at 0 ℃; for 4h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at 0 ℃; for 3.5h; Inert atmosphere;
DOI:10.1016/j.bmc.2020.115439