Benzenepropanethioic acid, a-[(triphenylmethyl)amino]-, S-2-pyridinyl ester, (S)-

Base Information

• Chemical Name: Benzenepropanethioic acid, a-[(triphenylmethyl)amino]-, S-2-pyridinyl ester, (S)-
• CAS No.: 112839-75-5
• Molecular Formula: C33H28N2OS
• Molecular Weight: 500.664
• Mol file: 112839-75-5.mol

Synonyms:

Chemical Property of Benzenepropanethioic acid, a-[(triphenylmethyl)amino]-, S-2-pyridinyl ester, (S)-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepropanethioic acid, a-[(triphenylmethyl)amino]-, S-2-pyridinyl ester, (S)-

There total 1 articles about Benzenepropanethioic acid, a-[(triphenylmethyl)amino]-, S-2-pyridinyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-Sulfanylpyridine (2637-34-5,73018-10-7) + N-trityl-L-phenylalanine (47672-25-3) → N-(triphenylmethyl)-L-phenylthioalanine S-2-pyridinyl ester (112839-75-5)

Guidance literature:

With dicyclohexyl-carbodiimide; In ethyl acetate; for 16h; Ambient temperature;

DOI:10.1021/jm00398a012

Reference yield: 82.6%

4-but-1-enylmagnesium bromide (7103-09-5) + N-(triphenylmethyl)-L-phenylthioalanine S-2-pyridinyl ester (112839-75-5) → 5-oxo-7-phenyl-6(S)-<(triphenylmethyl)amino>-1-heptene (112839-76-6)

Guidance literature:

In tetrahydrofuran; diethyl ether;

DOI:10.1021/jm00398a012

Reference yield:

N-(triphenylmethyl)-L-phenylthioalanine S-2-pyridinyl ester (112839-75-5) → 6(S)-amino-5-oxo-7-phenyl-1-heptene oxalate salt

Guidance literature:

Multi-step reaction with 2 steps

1: 82.6 percent / diethyl ether; tetrahydrofuran

2: 97 percent / acetic acid; H₂O / 5 h / Ambient temperature

In tetrahydrofuran; diethyl ether; water; acetic acid;

DOI:10.1021/jm00398a012

upstream raw materials:

2-Sulfanylpyridine

N-trityl-L-phenylalanine

Downstream raw materials:

5-oxo-7-phenyl-6(S)-<(triphenylmethyl)amino>-1-heptene