3-Chloro-4-methyl-7-hydroxycoumarin

Base Information

Chemical Name:3-Chloro-4-methyl-7-hydroxycoumarin
CAS No.:6174-86-3
Deprecated CAS:119739-80-9
Molecular Formula:C10H7 Cl O3
Molecular Weight:210.617
Hs Code.:2932209090
European Community (EC) Number:228-217-8
NSC Number:44204,24924
UNII:EVI89HA9V3
DSSTox Substance ID:DTXSID8052724
Nikkaji Number:J211.437B
Wikidata:Q27117921
Pharos Ligand ID:5HZP9NDK41U8
Metabolomics Workbench ID:55938
ChEMBL ID:CHEMBL589883
Mol file:6174-86-3.mol

Synonyms:3-chloro-4-methyl-7-hydroxycoumarin;chlorferon;chlorferron

Suppliers and Price of 3-Chloro-4-methyl-7-hydroxycoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Adipogen Life Sciences
3-Chloro-4-methyl-7-hydroxycoumarin ≥98%(HPLC)
5 g
$ 169.00

AHH
3-Chloro-4-methylumbelliferone 97%
10g
$ 297.00

American Custom Chemicals Corporation
3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN 95.00%
5G
$ 975.05

Biosynth Carbosynth
3-Chloro-7-hydroxy-4-methylcoumarin
10 g
$ 150.00

Biosynth Carbosynth
3-Chloro-7-hydroxy-4-methylcoumarin
25 g
$ 250.00

Biosynth Carbosynth
3-Chloro-7-hydroxy-4-methylcoumarin
2 g
$ 50.00

Chemenu
3-Chloro-7-hydroxy-4-methylcoumarin 96%
10g
$ 281.00

Chemenu
3-Chloro-7-hydroxy-4-methylcoumarin 96%
25g
$ 561.00

Chem-Impex
3-Chloro-7-hydroxy-4-methylcoumarin,≥98%(Assaybytitration) ≥98%(Assaybytitration)
5G
$ 479.55

Crysdot
3-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one 96%
10g
$ 297.00

Total 43 raw suppliers

Chemical Property of 3-Chloro-4-methyl-7-hydroxycoumarin

Chemical Property:

Vapor Pressure:3.63E-07mmHg at 25°C
Melting Point:240-244 °C(lit.)
Boiling Point:405.8°C at 760 mmHg
PKA:7.43±0.20(Predicted)
Flash Point:199.2°C
PSA：50.44000
Density:1.48g/cm³
LogP:2.46040
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:210.0083718
Heavy Atom Count:14
Complexity:298

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-4-methyl-7-hydroxycoumarin ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=C(C(=O)OC2=C1C=CC(=C2)O)Cl
Uses Labelled Chlorferon is has α-Glucosidase inhibitory antihyperglycemic activity of substituted chromenone derivatives. Also used in the synthesis of fluorogenic substrates for the detection of bacterial β-Galactosidase.

Technology Process of 3-Chloro-4-methyl-7-hydroxycoumarin

There total 9 articles about 3-Chloro-4-methyl-7-hydroxycoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

: 108-46-3
recorcinol

: 6174-86-3
3-chloro-4-methylumbelliferone

Guidance literature:: With trifluoroacetic acid; at 100 ℃; for 0.5h; regioselective reaction; Microwave irradiation;
DOI:10.1002/chem.201201039

Reference yield: 96.0%

: 4755-81-1,935731-92-3
methyl 2-chloroacetoacetate

: 108-46-3
recorcinol

: 6174-86-3
3-chloro-4-methylumbelliferone

Guidance literature:: With aluminum oxide; methanesulfonic acid; at 20 ℃; for 0.133333h;
DOI:10.1016/S0385-5414(07)81208-1

Reference yield: 83.5%

: 90-33-5,79566-13-5
7-hydroxy-4-methyl-chromen-2-one

: 6174-86-3
3-chloro-4-methylumbelliferone

Guidance literature:: With N-chloro-succinimide; copper(II) chloride monohydrate; zinc(II) chloride; In acetonitrile; at 82 ℃; for 0.05h; regioselective reaction;
DOI:10.1055/s-0037-1612080