Ethyl 2-chloroacetoacetate

Base Information Edit

Chemical Name:Ethyl 2-chloroacetoacetate
CAS No.:609-15-4
Deprecated CAS:121181-21-3,150010-45-0,150010-45-0
Molecular Formula:C6H9ClO3
Molecular Weight:164.589
Hs Code.:29183000
European Community (EC) Number:210-180-4
NSC Number:78426
UNII:A9GFN94N9A
DSSTox Substance ID:DTXSID3049330
Nikkaji Number:J60.802E
ChEMBL ID:CHEMBL3186400
Mol file:609-15-4.mol

Synonyms:A 21960;A-21960

Suppliers and Price of Ethyl 2-chloroacetoacetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-Chloracetoacetate
250g
$ 275.00

TRC
Ethyl2-Chloracetoacetate
50g
$ 120.00

TCI Chemical
Ethyl 2-Chloroacetoacetate >95.0%(GC)
25g
$ 16.00

TCI Chemical
Ethyl 2-Chloroacetoacetate >95.0%(GC)
500g
$ 97.00

SynQuest Laboratories
Ethyl 2-chloroacetoacetate
100 g
$ 100.00

SynQuest Laboratories
Ethyl 2-chloroacetoacetate
500 g
$ 157.00

Sigma-Aldrich
Ethyl 2-chloroacetoacetate produced by Wacker Chemie AG, Burghausen, Germany, ≥96% (GC)
25kg
$ 1040.00

Sigma-Aldrich
Ethyl 2-chloroacetoacetate 95%
500g
$ 84.90

Sigma-Aldrich
Ethyl 2-chloroacetoacetate produced by Wacker Chemie AG, Burghausen, Germany, ≥96% (GC)
1kg
$ 68.10

Sigma-Aldrich
Ethyl 2-chloroacetoacetate 95%
100g
$ 37.70

Total 163 raw suppliers

Chemical Property of Ethyl 2-chloroacetoacetate Edit

Chemical Property:

Appearance/Colour:clear bright yellow liquid
Vapor Pressure:0.086mmHg at 25°C
Melting Point:-80 °C
Refractive Index:n20/D 1.441(lit.)
Boiling Point:225.5 °C at 760 mmHg
PKA:7.92±0.46(Predicted)
Flash Point:50 °C
PSA：43.37000
Density:1.176 g/cm³
LogP:0.74590
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility.:17 g/L (20 ºC)
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:164.0240218
Heavy Atom Count:10
Complexity:144

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-Chloracetoacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, Xn, F
Hazard Codes:C,Xn,F
Statements: 10-22-34-52/53-36/37/38-36
Safety Statements: 16-26-36/37/39-45-61-37/39

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Halogenated Esters
Canonical SMILES:CCOC(=O)C(C(=O)C)Cl
Uses Ethyl 2-chloroacetoacetate was used to study reductive dechlorination of β-keto ester ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae.

Technology Process of Ethyl 2-chloroacetoacetate

There total 26 articles about Ethyl 2-chloroacetoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 141-97-9
ethyl acetoacetate

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

Guidance literature:: With thionyl chloride; In tetrachloromethane; at 20 ℃; for 1h;
DOI:10.1002/jhet.2302

Reference yield: 97.0%

: 141-97-9
ethyl acetoacetate

: 6134-66-3
ethyl 2,2-dichloroacetoacetate

: 85153-67-9
ethyl 2,2,4-trichloro-3-oxobutyrate

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

Guidance literature:: With chlorine; at 55 - 60 ℃; for 9h; Product distribution; Mechanism; dinamics of chlorination of acetoacetic ester, products in the mixture on the time;

Reference yield: 46.0%

: 20412-62-8,66279-49-0
ethyl 3-oxobutanate sodium salt

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

Guidance literature:: With tetrachloromethane; In dimethyl sulfoxide; for 16h; Heating; at 20 - 25 deg C in different bipolar aprotic solvents;