1-(Oxolan-2-yl)-2-phenylethanone

Base Information

Chemical Name:1-(Oxolan-2-yl)-2-phenylethanone
CAS No.:113122-86-4
Molecular Formula:C12H14O2
Molecular Weight:190.242
Hs Code.:
DSSTox Substance ID:DTXSID40551006
Mol file:113122-86-4.mol

Synonyms:113122-86-4;1-(oxolan-2-yl)-2-phenylethanone;Ethanone, 2-phenyl-1-(tetrahydro-2-furanyl)-;1-(Oxolan-2-yl)-2-phenylethan-1-one;2-phenyl-1-(tetrahydrofuran-2-yl)ethanone;2-phenyl-1-tetrahydro-2-furanylethanone;SCHEMBL1515881;DTXSID40551006;JIXMTHYSMVUUBS-UHFFFAOYSA-N;AKOS010311794;2-Phenyl-1-(tetrahydro-2-furanyl)ethanone;CS-0236257;G46398;EN300-1699221

Suppliers and Price of 1-(Oxolan-2-yl)-2-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(Oxolan-2-yl)-2-phenylethanone

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:190.099379685
Heavy Atom Count:14
Complexity:195

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(OC1)C(=O)CC2=CC=CC=C2

Technology Process of 1-(Oxolan-2-yl)-2-phenylethanone

There total 5 articles about 1-(Oxolan-2-yl)-2-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 113122-76-2
2-[3-(3-Benzenesulfinyl-3-benzyl-oxiranyl)-propoxy]-tetrahydro-pyran

: 113122-86-4
2-phenyl-1-(tetrahydrofuran-2-yl)ethan-1-one

Guidance literature:: In ethanol; at 50 ℃; for 0.5h; Heating;
DOI:10.1016/S0040-4039(00)96159-8

Reference yield: 46.0%

: 109-99-9,24979-97-3,77392-70-2
tetrahydrofuran

: 103-80-0
phenylacetyl chloride

: 113122-86-4
2-phenyl-1-(tetrahydrofuran-2-yl)ethan-1-one

Guidance literature:: With potassium phosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; C₁₈H₂₄N₂*NiCl₂; at 20 ℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1021/acs.orglett.7b01552

Reference yield:

: 7681-84-7
tetrahydrofuran-2-carbaldehyde

: 66310-10-9
N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate

: 113122-86-4
2-phenyl-1-(tetrahydrofuran-2-yl)ethan-1-one

Guidance literature:: N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate; With potassium phosphate; (1,2-dimethoxyethane)dichloronickel(II); tetrakis(tetrabutylammonium)decatungstate(VI); 4,4'-di-tert-butyl-2,2'-bipyridine; In acetonitrile; at 25 ℃; for 0.166667h; Inert atmosphere;

tetrahydrofuran-2-carbaldehyde; In acetonitrile; at 25 ℃; for 15h; regioselective reaction; Irradiation; Inert atmosphere;
DOI:10.1021/acs.orglett.1c01716