ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate

Base Information

Chemical Name:ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate
CAS No.:173908-47-9
Molecular Formula:C₁₇H₁₅ClN₂O₄S
Molecular Weight:378.836
Hs Code.:
Mol file:173908-47-9.mol

Synonyms:ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate

Suppliers and Price of ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate

Chemical Property:

Vapor Pressure:3.39E-14mmHg at 25°C
Boiling Point:596.6°Cat760mmHg
Flash Point:314.6°C
PSA：99.77000
Density:1.45g/cm³
LogP:4.95260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate

There total 3 articles about ethyl 1-(2-amino-5-chloro-phenyl)sulfonylindole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 173908-27-5
1-(5-Chloro-2-nitro-benzenesulfonyl)-1H-indole-2-carboxylic acid ethyl ester

: 173908-47-9
1-(2-Amino-5-chloro-benzenesulfonyl)-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With iron; acetic acid; at 60 ℃; for 2h;
DOI:10.1021/jm950568w

Reference yield:

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 173908-47-9
1-(2-Amino-5-chloro-benzenesulfonyl)-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 16 percent / 50percent aq. KOH, n-tetrabutylammonium hydrogen sulfate

2: 50 percent / iron power, glacial acetic acid / 2 h / 60 °C

With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; iron; acetic acid;
DOI:10.1021/jm950568w

Reference yield:

: 21792-87-0
5-chloro-2-nitrobenzenesulfonyl chloride

: 173908-47-9
1-(2-Amino-5-chloro-benzenesulfonyl)-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 16 percent / 50percent aq. KOH, n-tetrabutylammonium hydrogen sulfate

2: 50 percent / iron power, glacial acetic acid / 2 h / 60 °C

With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; iron; acetic acid;
DOI:10.1021/jm950568w