METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE)

Base Information

• Chemical Name: METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE)
• CAS No.: 56252-55-2
• Molecular Formula: C31H49 Al O2
• Molecular Weight: 480.71
• Mol file: 56252-55-2.mol

Synonyms:Bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum;Bis(2,6-di-tert-butyl-4-methylphenoxy)methylaluminum;Bis[2,6-bis(1,1-dimethylethyl)-4-methylphenolato]methylaluminum; MAD; MAD(reagent); Methylaluminum bis(2,6-di-tert-butyl-4-methylphenolate);Methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide); methylaluminumbis(2,6-di-tert-butyl-4-methylphenoxide)

Chemical Property of METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE)

Chemical Property:

• Boiling Point: 90-92 °C(Press: 1 Torr)
• PSA: 18.46000
• Density: 0.94
• LogP: 9.12160
• Storage Temp.: Refrigerator

Purity/Quality:

98%Min ^*data from raw suppliers

METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE) (0.4MOL/L IN TOLUENE) 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 11-34
• Safety Statements: 3/7-9-16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE)

There total 5 articles about METHYLALUMINUM BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,6-di-tert-butyl-4-methyl-phenol (128-37-0) + trimethylaluminum (75-24-1) → bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum (56252-55-2)

Guidance literature:

In hexane; (Ar); std. Schlenk technique; soln. of Me3Al in hexane was slowly added over 5 min to stirred soln. of phenol in hexane; soln. was stirred at 25°C for 1 h; evapd. in vac. overnight;

DOI:10.1021/om060474s

Reference yield:

MeAl(H2O)(O(2,6-di-tert-butyl-4-methylphenyl))2*2C4D8O → bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum (56252-55-2)

Guidance literature:

In tetrahydrofuran-d8; byproducts: 2,6-di-tert-butyl-4-methylphenol, CH4; at temp. above 0°C; monitored by NMR; Kinetics;

DOI:10.1021/ja030121+

Reference yield:

trimethylaluminium dimer + 2,6-di-tert-butyl-4-methyl-phenol (128-37-0) → bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum (56252-55-2)

Guidance literature:

In hexane; addn. of Me3Al in hexane to a soln. of 2,6-di-t-butyl-4-methylphenol in degassed hexane at room temp. under Ar (white ppt.); react. for 1 h; heating until the ppt. redissolves in hexane; storing resulting soln. for 3 h; crystn.; filtration in an argon box;

DOI:10.1246/bcsj.65.541

upstream raw materials:

2,6-di-tert-butyl-4-methyl-phenol

trimethylaluminum

2,6-di-t-butyl-4-methylphenol anionic form

Downstream raw materials:

(CH₃C₆H₂(C(CH₃)3)2O)2Al(CH₃)(P(CH₃)3)

dimethylaluminum 2,6-di-tert-butyl-4-methylphenoxide

Al(C₆H₂(CH₃)(C(CH₃)3)O)2(OC(NMe)Ph)-cyclic

Refernces

• 1、 Zaccaria, Francesco,Zuccaccia, Cristiano,Cipullo, Roberta,Macchioni, Alceo. "Extraction of Reliable Molecular Information from Diffusion NMR Spectroscopy: Hydrodynamic Volume or Molecular Mass?". . p. 9930 - 9937. Retrieved 2019.
• 2、 Stapleton, Russell A.,Al-Humydi, Abdulaziz,Chai, Jianfang,Galan, Brandon R.,Collins, Scott. "Sterically hindered aluminum alky is: Weakly interacting scavenging agents of use in olefin polymerization". . p. 5083 - 5092. Retrieved 2006.
• 3、 Luo, Yunfei,Wales, Steven M.,Korkis, Stamatis E.,Roy, Iain D.,Lewis, William,Lam, Hon Wai. "Switchable Synthesis of Z-Homoallylic Boronates and E-Allylic Boronates by Enantioselective Copper-Catalyzed 1,6-Boration". supporting information. p. 8315 - 8319. Retrieved 2018/05/30.