SALICYLIDENE 2-AMINOPYRIDINE

Base Information

• Chemical Name: SALICYLIDENE 2-AMINOPYRIDINE
• CAS No.: 1823-47-8
• Molecular Formula: C12H10N2O
• Molecular Weight: 198.224
• Hs Code.: 2933399090
• Mol file: 1823-47-8.mol

Synonyms:Phenol,o-(N-2-pyridylformimidoyl)- (6CI,7CI,8CI);2-(Salicylideneamino)pyridine;N-2-Pyridylsalicylideneamine;N-Pyridylsalicylideneamine;N-Salicylidene-2-aminopyridine;N-Salicylidene-2-pyridinamine;N-Salicylidene-o-aminopyridine;NSC 96380;Salicylidene-2-pyridineamine;o-[(o-Hydroxybenzylidene)amino]pyridine;2-[(E)-(Pyridin-2-ylimino)methyl]phenol;Phenol, 2-[(E)-(2-pyridinylimino)methyl]-;Salicylidene 2-Aminopyridine;α-(2-Pyridylimino)-o-cresol;

Chemical Property of SALICYLIDENE 2-AMINOPYRIDINE

Chemical Property:

• Vapor Pressure: 7.42E-06mmHg at 25°C
• Melting Point: 185-186 °C
• Refractive Index: 1.758
• Boiling Point: 369.618 °C at 760 mmHg
• PKA: 8.51±0.35(Predicted)
• Flash Point: 177.339 °C
• PSA: 45.48000
• Density: 1.13 g/cm³
• LogP: 2.53780

Purity/Quality:

98%,99%, ^*data from raw suppliers

Salicylidene 2-aminopyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SALICYLIDENE 2-AMINOPYRIDINE

There total 7 articles about SALICYLIDENE 2-AMINOPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-aminopyridine (504-29-0) + salicylaldehyde (90-02-8) → 2-(pyridine-2-yliminomethyl)phenol (1823-47-8)

Guidance literature:

In neat (no solvent); at 20 ℃; for 0.166667h; Green chemistry;

Reference yield: 93.0%

2-aminopyridine (504-29-0) + salicylaldehyde (90-02-8) → (Z)-2-((pyridin-2-ylimino)methyl)phenol (1823-47-8,17543-97-4)

Guidance literature:

In ethanol; at 20 ℃; for 4h;

DOI:10.1002/aoc.6484

Reference yield: 76.0%

2-aminopyridine (504-29-0) + 2-methyl-benzyl alcohol (89-95-2) → 2-(pyridine-2-yliminomethyl)phenol (1823-47-8)

Guidance literature:

In tetrahydrofuran; for 1h; Heating;

DOI:10.1016/S0022-2860(00)00393-8

upstream raw materials:

2-aminopyridine

salicylaldehyde

2-methyl-benzyl alcohol

pyridine

Downstream raw materials:

[RuBr₂(P(C₆H₅)3)2(OC₆H₄CHNC₅H₄N)]

CrCl(OC₆H₄CHNC₅H₄N)(OH)(H₂O)2*H₂O

[RuBr₂(As(C₆H₅)3)2(OC₆H₄CHNC₅H₄N)]

[RuCl₂(As(C₆H₅)3)2(OC₆H₄CHNC₅H₄N)]

Refernces

• 1、 Zhang, Yuan-Zhu,Brown, Andrew J.,Meng, Yin-Shan,Sun, Hao-Ling,Gao, Song. "Linear trinuclear cobalt(ii) single molecule magnet". . p. 2865 - 2870. Retrieved 2015.
• 2、 Cimerman, Z.,Kiralj, R.,Galic, N.. "The structure and tautomeric properties of 2-(3-pyridylmethyliminomethyl)phenol". . p. 7 - 14. Retrieved 1994.
• 3、 Giri, Sanjib,Biswas, Saptarshi,Drew, Michael G.B.,Ghosh, Ashutosh,Saha, Shyamal K.. "Structure and magnetic properties of a tetranuclear Cu(II) complex containing the 2-(pyridine-2-yliminomethyl)-phenol ligand". . p. 152 - 156. Retrieved 2011.
• 4、 Tantaru, Gladiola,Popescu, Maria-Cristina,Bild, Veronica,Poiata, Antonia,Lisa, Gabriela,Vasile, Cornelia. "Spectroscopic, thermal and antimicrobial properties of the copper(II) complex of Schiff base derived from 2-(salicylidene) aminopyridine". . p. 356 - 361. Retrieved 2012.
• 5、 Dubey, Raj Kumar,Singh, Avadhesh Pratap,Dwivedi, Nalini. "Synthesis and physicochemical characterization of some hexacoordinated tin(IV) Schiff base complexes". . p. 77 - 83. Retrieved 2011.
• 6、 Dubey, Raj Kumar,Singh, Avadhesh Pratap,Jaiswal, Nitesh,Singh, Divya Pratap,Meenakshi,Kushwaha, Ajeet Kumar,Kumar, Manoj,Anjum, Afreen. "Synthesis, spectroscopic characterization, DFT calculations, and antimicrobial activities of N-arylsalicylaldiminate derivatives of diorganotin(IV)". . p. 3371 - 3384. Retrieved 2019.
• 7、 Abdel-Rahman, Laila H.,Basha, Maram T.,Al-Farhan, Badriah Saad,Shehata, Mohamed R.,Abdalla, Ehab M.. "Synthesis, characterization, potential antimicrobial, antioxidant, anticancer, DNA binding, and molecular docking activities and DFT on novel Co(II), Ni(II), VO(II), Cr(III), and La(III) Schiff base complexes". . . Retrieved 2021/11/01.
• 8、 Younis, Osama,El-Katori, Emad E.,Hassanien, Reda,Abousalem, Ashraf S.,Tsutsumi, Osamu. "Luminescent coatings: White-color luminescence from a simple and single chromophore with high anticorrosion efficiency". . . Retrieved 2019/12/24.