2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one

Base Information

Chemical Name:2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one
CAS No.:113478-79-8
Molecular Formula:C15H12BrClO
Molecular Weight:323.617
Hs Code.:
DSSTox Substance ID:DTXSID50550242
Mol file:113478-79-8.mol

Synonyms:113478-79-8;2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one;DTXSID50550242

Suppliers and Price of 2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:321.97601
Heavy Atom Count:18
Complexity:268

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C(CC2=CC=C(C=C2)Cl)Br

Technology Process of 2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one

There total 4 articles about 2-Bromo-3-(4-chlorophenyl)-1-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: C₂₂H₁₆BrClO₂

: 113478-79-8
2-bromo-3-(4-chlorophenyl)-1-phenylpropane-1-one

Guidance literature:: With silica-supported sulfuric acid; In 1,2-dichloro-ethane; at 80 ℃; for 1h;
DOI:10.1246/cl.2011.484

Reference yield: 82.0%

: 5739-39-9
3-(4-chlorophenyl)-1-phenylpropan-1-one

: 113478-79-8
2-bromo-3-(4-chlorophenyl)-1-phenylpropane-1-one

Guidance literature:: With bromine; In acetic acid; at 50 ℃;
DOI:10.1007/BF00486920

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 113478-79-8
2-bromo-3-(4-chlorophenyl)-1-phenylpropane-1-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / ethanol; water / 0.17 h / 20 °C

1.2: 20 °C

2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3.1: aluminum (III) chloride; bromine / chloroform / 20 °C

With aluminum (III) chloride; palladium on activated charcoal; hydrogen; bromine; sodium hydroxide; In ethanol; chloroform; water; ethyl acetate;
DOI:10.1016/j.ejmech.2016.07.047