Benzeneacetic acid, a-(methylamino)-, hydrochloride(1:1)

Base Information

• Chemical Name: Benzeneacetic acid, a-(methylamino)-, hydrochloride(1:1)
• CAS No.: 28544-42-5
• Molecular Formula: C9H11 N O2 . Cl H
• Molecular Weight: 201.653
• Mol file: 28544-42-5.mol

Synonyms:Benzeneaceticacid, a-(methylamino)-, hydrochloride(9CI); Sarcosine, 2-phenyl-, hydrochloride (7CI,8CI); NSC 117412; a-Phenylsarcosine hydrochloride

Chemical Property of Benzeneacetic acid, a-(methylamino)-, hydrochloride(1:1)

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetic acid, a-(methylamino)-, hydrochloride(1:1)

There total 10 articles about Benzeneacetic acid, a-(methylamino)-, hydrochloride(1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.1%

α-Methylamino-phenylacetamid-hydrochlorid → 2-(methylamino)-2-phenylethanoic acid hydrochloride (28544-42-5)

Guidance literature:

With hydrogenchloride; for 1h; Heating;

DOI:10.1002/hlca.19800630312

Reference yield: 96.0%

C9H10N2*ClH (5537-52-0) → 2-(methylamino)-2-phenylethanoic acid hydrochloride (28544-42-5)

Guidance literature:

With hydrogenchloride; water; at 110 ℃; for 23h;

DOI:10.1021/acs.orglett.9b01580

Reference yield: 73.0%

carbon monoxide (201230-82-2) + N-Benzylidenemethylamine (622-29-7) → phenylacetic acid (103-82-2) + C25H24N2O2 + 2-(methylamino)-2-phenylethanoic acid hydrochloride (28544-42-5)

Guidance literature:

carbon monoxide; N-Benzylidenemethylamine; tetracarbonyl(phenylacetyl)cobalt; In 1,4-dioxane; hexane; at 50 ℃; for 6h; under 41372.9 Torr;

With hydrogenchloride; for 24h; Further stages.; Heating;

DOI:10.1002/anie.200700646

upstream raw materials:

2-methoxycarbonyl-N-methyl-2-phenylglycine

α-(Methylamino)-phenylacetonitril

(RS)-mandelonitrile

carbon monoxide

Downstream raw materials:

phenylglyoxylic acid ethyl ester

benzoic acid ethyl ester

N-(2-chlorobenzoyl)-N-methyl-C-phenylglycine

N-(4-fluorobenzoyl)-N-methyl-C-phenylglycine