(S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol

Base Information

Chemical Name:(S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol
CAS No.:97549-54-7
Molecular Formula:C₁₃H₁₉NO₃
Molecular Weight:237.299
Hs Code.:
DSSTox Substance ID:DTXSID00913868
Nikkaji Number:J707.250C
Wikidata:Q82884577
Mol file:97549-54-7.mol

Synonyms:N-methylcalycotomine

Suppliers and Price of (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol

Chemical Property:

Vapor Pressure:1.08E-05mmHg at 25°C
Boiling Point:356.2°Cat760mmHg
Flash Point:169.2°C
PSA：41.93000
Density:1.109g/cm³
LogP:1.16300
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:237.13649347
Heavy Atom Count:17
Complexity:249

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C(C=C2C1CO)OC)OC
Isomeric SMILES:CN1CCC2=CC(=C(C=C2[C@H]1CO)OC)OC

Technology Process of (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol

There total 31 articles about (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1-Ethoxycarbonyl-6,7-dimethoxy-2-methyl-3,4-dihydro-isoquinolinium; iodide

: 93598-34-6,97549-54-7
(+/-)-N-methylcalycotomine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Heating;
DOI:10.1071/CH9841659

Reference yield: 91.0%

: 173266-44-9
(S)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid methyl ester

: 101053-32-1,97549-54-7
(R)-(-)-N-methylcalycotomine

: 97549-54-7
(S)-(+)-N-methylcalycotomine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Title compound not separated from byproducts; Heating;
DOI:10.3987/COM-99-8681

Reference yield: 91.0%

: 173266-44-9
(S)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid methyl ester

: 101053-32-1,97549-54-7
(R)-(-)-N-methylcalycotomine

: 97549-54-7
(S)-(+)-N-methylcalycotomine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Title compound not separated from byproducts; Heating;
DOI:10.3987/COM-99-8681