7-Oxodihydrokarounidiol

Base Information

Chemical Name:7-Oxodihydrokarounidiol
CAS No.:143183-47-5
Molecular Formula:C₃₀H₄₈O₃
Molecular Weight:456.709
Hs Code.:
DSSTox Substance ID:DTXSID20931766
Nikkaji Number:J465.088C
Wikidata:Q82907350
Mol file:143183-47-5.mol

Synonyms:7-oxo-DC-friedo-olean-8-ene-3 alpha,29-diol;7-oxodihydrokarounidiol

Suppliers and Price of 7-Oxodihydrokarounidiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-Oxodihydrokarounidiol

Chemical Property:

Vapor Pressure:7.24E-15mmHg at 25°C
Boiling Point:559.9°C at 760 mmHg
Flash Point:306.5°C
PSA：57.53000
Density:1.1g/cm³
LogP:6.46440
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:456.36034539
Heavy Atom Count:33
Complexity:902

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(CCC2(C1CC(=O)C3=C2CCC4(C3(CCC5(C4CC(CC5)(C)CO)C)C)C)C)O)C
Isomeric SMILES:C[C@]12CC[C@@](C[C@H]1[C@@]3(CCC4=C([C@]3(CC2)C)C(=O)C[C@@H]5[C@@]4(CC[C@H](C5(C)C)O)C)C)(C)CO

Technology Process of 7-Oxodihydrokarounidiol

There total 2 articles about 7-Oxodihydrokarounidiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Benzoic acid (3R,4aR,6bS,8aS,11R,12aR,12bS,14bS)-11-acetoxymethyl-4,4,6b,8a,11,12b,14b-heptamethyl-6-oxo-1,2,3,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14b-icosahydro-picen-3-yl ester

: 143183-47-5
7-oxodihydrokarounidiol

: Benzoic acid (3R,4aR,6bS,8aS,11R,12aR,12bS,14bS)-11-hydroxymethyl-4,4,6b,8a,11,12b,14b-heptamethyl-6-oxo-1,2,3,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14b-icosahydro-picen-3-yl ester

Guidance literature:: With potassium hydroxide; In methanol; for 8h; Ambient temperature;
DOI:10.1016/S0031-9422(97)00433-0

Reference yield:

: 7-oxo-8β-D:C-friedo-olean-9(11)-ene-3α,29-diol diacetate

: 143183-47-5
7-oxodihydrokarounidiol

Guidance literature:: With potassium hydroxide; In methanol; Ambient temperature;
DOI:10.1248/cpb.42.1101

Reference yield:

: 143183-47-5
7-oxodihydrokarounidiol

: 24480-44-2
bryononic acid

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine / Ambient temperature

2: 1.) hydrazine hydrate, 2.) KOH, 3.) Ac₂O, pyridine

3: SeO₂, AcOH / 24 h / Heating

4: 1.) Li, ethylenediamine, 2.) Ac₂O, pyridine / 1.) reflux, 2 h, 2.) RT, overnight

5: 6 mg / KOH / methanol / 4 h / Ambient temperature

6: 14 mg / CrO₃*pyridine / Ambient temperature

With pyridine; potassium hydroxide; selenium(IV) oxide; chromium trioxide-pyridine complex; acetic anhydride; lithium; hydrazine hydrate; acetic acid; ethylenediamine; In methanol;
DOI:10.1248/cpb.40.1199