Methyl 2-bromo-6-hydroxybenzoate

Base Information

Chemical Name:Methyl 2-bromo-6-hydroxybenzoate
CAS No.:113763-37-4
Molecular Formula:C8H7BrO3
Molecular Weight:231.046
Hs Code.:
DSSTox Substance ID:DTXSID00602169
Mol file:113763-37-4.mol

Synonyms:methyl 2-bromo-6-hydroxybenzoate;113763-37-4;Benzoic acid, 2-bromo-6-hydroxy-, methyl ester;MFCD18398784;2-BROMO-6-HYDROXYBENZOIC ACID METHYL ESTER;SCHEMBL4144207;methyl2-bromo-6-hydroxybenzoate;DTXSID00602169;WIRCWLQPIBGDQH-UHFFFAOYSA-N;BS-19246;SY355314;DB-091669;2-Bromo-6-hydroxy-benzoic acid methyl ester

Suppliers and Price of Methyl 2-bromo-6-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Methyl 2-bromo-6-hydroxybenzoate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:229.95786
Heavy Atom Count:12
Complexity:172

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=CC=C1Br)O

Technology Process of Methyl 2-bromo-6-hydroxybenzoate

There total 3 articles about Methyl 2-bromo-6-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 914298-83-2
2-bromo-6-{[tert-butyl(dimethyl)silyl]oxy}-N,N-diethylbenzamide

: 420-37-1
trimethoxonium tetrafluoroborate

: 113763-37-4
methyl 2-bromo-6-hydroxybenzoate

Guidance literature:: With disodium hydrogenphosphate; In acetonitrile; at 20 ℃; for 16h; Product distribution / selectivity;

Reference yield:

: 19311-91-2
N,N-diethylsalicylamide

: 113763-37-4
methyl 2-bromo-6-hydroxybenzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 20 °C

2.1: n-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C

2.2: 20.5 h / -78 - 20 °C

3.1: disodium hydrogenphosphate / acetonitrile / 16 h / 20 °C

With disodium hydrogenphosphate; n-butyllithium; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile; pentane;

Reference yield:

: 721448-74-4
2-{[tert-butyl(dimethyl)silyl]oxy}-N,N-diethylbenzamide

: 113763-37-4
methyl 2-bromo-6-hydroxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C

1.2: 20.5 h / -78 - 20 °C

2.1: disodium hydrogenphosphate / acetonitrile / 16 h / 20 °C

With disodium hydrogenphosphate; n-butyllithium; In tetrahydrofuran; acetonitrile; pentane;