4-Dodecyloxy-2-hydroxybenzophenone

Base Information

• Chemical Name: 4-Dodecyloxy-2-hydroxybenzophenone
• CAS No.: 2985-59-3
• Deprecated CAS: 117743-90-5,55963-32-1,2375272-76-5,55963-32-1
• Molecular Formula: C25H34 O3
• Molecular Weight: 382.543
• European Community (EC) Number: 221-049-6
• DSSTox Substance ID: DTXSID6062755
• Nikkaji Number: J47.620J
• Wikidata: Q63391911
• Mol file: 2985-59-3.mol

Synonyms:2985-59-3;4-Dodecyloxy-2-hydroxybenzophenone;4-(DODECYLOXY)-2-HYDROXY BENZOPHENONE;(4-(Dodecyloxy)-2-hydroxyphenyl)(phenyl)methanone;(4-dodecoxy-2-hydroxyphenyl)-phenylmethanone;EINECS 221-049-6;Methanone, [4-(dodecyloxy)-2-hydroxyphenyl]phenyl-;Methanone, (4-(dodecyloxy)-2-hydroxyphenyl)phenyl-;[4-(dodecyloxy)-2-hydroxyphenyl](phenyl)methanone;Benzophenone, 4-dodecyloxy-2-hydroxy-;2-benzoyl-5-(dodecyloxy)phenol;2-hydroxy-4-dodecyloxybenzophenone;SCHEMBL38596;DTXSID6062755;2-hydroxy-4-dodecyloxybenzophenon;4-dodecyloxy-2-hydroxy-benzophenone;MFCD00026578;AKOS015889878;2-Hydroxy-4-(dodecyloxy) benzophenone;Benzophenone, 4-(dodecyloxy)-2-hydroxy-;FT-0634588;A820076;Q63391911

Chemical Property of 4-Dodecyloxy-2-hydroxybenzophenone

Chemical Property:

• Vapor Pressure: 7.13E-11mmHg at 25°C
• Melting Point: 49-50 °C
• Refractive Index: 1.534
• Boiling Point: 506.3°Cat760mmHg
• PKA: 7.58±0.35(Predicted)
• Flash Point: 163.6°C
• PSA: 46.53000
• Density: 1.029g/cm³
• LogP: 6.92290
• XLogP3: 9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 382.25079494
• Heavy Atom Count: 28
• Complexity: 403

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-(Dodecyloxy)-2-hydroxyphenyl)(phenyl)methanone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O

Technology Process of 4-Dodecyloxy-2-hydroxybenzophenone

There total 4 articles about 4-Dodecyloxy-2-hydroxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2.4-dihydroxybenzophenone (131-56-6) + 1-dodecylbromide (143-15-7) → 4-dodecyloxy-2-hydroxybenzophenone (2985-59-3)

Guidance literature:

With potassium carbonate; In acetone; for 20h; Heating;

DOI:10.1002/prac.19923340313

Reference yield:

benzoyl chloride (98-88-4) → 4-dodecyloxy-2-hydroxybenzophenone (2985-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / 1,2-dichloro-ethane / 5 h / 65 °C

2: K₂CO₃ / acetone / 20 h / Heating

With aluminium trichloride; potassium carbonate; In 1,2-dichloro-ethane; acetone;

DOI:10.1002/prac.19923340313

Reference yield:

recorcinol (108-46-3) → 4-dodecyloxy-2-hydroxybenzophenone (2985-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / 1,2-dichloro-ethane / 5 h / 65 °C

2: K₂CO₃ / acetone / 20 h / Heating

With aluminium trichloride; potassium carbonate; In 1,2-dichloro-ethane; acetone;

DOI:10.1002/prac.19923340313

upstream raw materials:

2.4-dihydroxybenzophenone

1-dodecylbromide

benzoyl chloride

recorcinol

Downstream raw materials:

2-(2-Diethylamino-ethoxy)-4-dodecyloxy-benzophenon

2-(4-Chlor-phenyl)-1-[2-(2-diethylamino-ethoxy)-4-dodecyloxy-phenyl]-1-phenyl-ethanol

Refernces

• 1、 Beger, J.,Binte, H.-J.,Brunne, L.,Neumann, R.. "Synthese von 4-Alkoxy-2-hydroxyphenylketoximen als Metallextraktions-Reagenzien". . p. 269 - 277. Retrieved 2007/10/02.