Phenyl(pyrrolidin-2-yl)methanol

Base Information

Chemical Name:Phenyl(pyrrolidin-2-yl)methanol
CAS No.:113864-94-1
Molecular Formula:C11H15NO
Molecular Weight:177.246
Hs Code.:
European Community (EC) Number:819-993-4
Wikidata:Q107964360
Mol file:113864-94-1.mol

Synonyms:phenyl(pyrrolidin-2-yl)methanol;113864-94-1;(R)-Phenyl((S)-pyrrolidin-2-yl)methanol;2-(Hydroxy(phenyl)methyl)pyrrolidine;SCHEMBL5177411;YPMHBZQROFTOSU-UHFFFAOYSA-N;alpha-phenyl-2-pyrrolidine methanol;AKOS013407201;SB46664;SB48057;FT-0723880;EN300-331994;Z1192039732

Suppliers and Price of Phenyl(pyrrolidin-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Phenyl(pyrrolidin-2-yl)methanol

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.115364102
Heavy Atom Count:13
Complexity:154

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C(C2=CC=CC=C2)O

Technology Process of Phenyl(pyrrolidin-2-yl)methanol

There total 10 articles about Phenyl(pyrrolidin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 89656-32-6
{1-[(E)-tert-Butylimino-methyl]-pyrrolidin-2-yl}-phenyl-methanol

: 113864-94-1
L-2-{(R,S)-1-hydroxy-1-phenylmethyl}pyrrolidine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 12h; Heating;
DOI:10.1021/ja00323a035

Reference yield:

: 562101-63-7
N-boc-2-(hydroxy(phenyl)-methyl)pyrrolidine

: 113864-94-1
2-(hydroxy(phenyl)methyl)pyrrolidine

Guidance literature:: With trifluoroacetic acid; In dichloromethane;

Reference yield:

: 100-52-7
benzaldehyde

: 113864-94-1
L-2-{(R,S)-1-hydroxy-1-phenylmethyl}pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) t-BuLi / 1.) THF, -20 deg C, 1 h; 2.) THF, -78 -> 0 deg C, 3 h

2: 89 percent / LiAlH₄ / tetrahydrofuran / 12 h / Heating

With lithium aluminium tetrahydride; tert.-butyl lithium; In tetrahydrofuran;
DOI:10.1021/ja00323a035