N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine

Base Information

• Chemical Name: N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine
• CAS No.: 80259-18-3
• Deprecated CAS: 142402-85-5
• Molecular Formula: C24H24N4
• Molecular Weight: 368.481
• DSSTox Substance ID: DTXSID70230190
• Nikkaji Number: J2.076.661A
• Wikidata: Q83110621
• Pharos Ligand ID: WRA7P5X4XUUX
• ChEMBL ID: CHEMBL106525
• Mol file: 80259-18-3.mol

Synonyms:acridin-9-yl-(4-(4-methylpiperazin-1-yl)-phenyl)amine;JP-1302

Chemical Property of N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine

Chemical Property:

• Vapor Pressure: 3.49E-12mmHg at 25°C
• Boiling Point: 550.9°Cat760mmHg
• Flash Point: 287°C
• PSA: 31.40000
• Density: 1.227g/cm³
• LogP: 4.95930
• Storage Temp.: Desiccate at -20°C
• XLogP3: 5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 368.20009678
• Heavy Atom Count: 28
• Complexity: 473

Purity/Quality:

98%Min ^*data from raw suppliers

JP 1302 dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCN(CC1)C2=CC=C(C=C2)NC3=C4C=CC=CC4=NC5=CC=CC=C53
• Uses: JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.

Technology Process of N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine

There total 1 articles about N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

9-Chloroacridine (1207-69-8) + 4-(4-Methyl-piperazino)-anilin (16153-81-4) → MMV006172 (80259-18-3)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane;

upstream raw materials:

9-Chloroacridine

4-(4-Methyl-piperazino)-anilin

Refernces