N-(1-methylpiperidin-4-yl)benzamide

Base Information

Chemical Name:N-(1-methylpiperidin-4-yl)benzamide
CAS No.:1141-58-8
Molecular Formula:C13H18N2O
Molecular Weight:218.299
Hs Code.:
DSSTox Substance ID:DTXSID80361348
Nikkaji Number:J950.071E
Wikidata:Q82143646
Mol file:1141-58-8.mol

Synonyms:N-(1-methylpiperidin-4-yl)benzamide;1141-58-8;SCHEMBL363917;DTXSID80361348;STK462303;AKOS003354060;N-(1-Methylpiperidine-4-yl)benzamide;SR-01000291350;SR-01000291350-1

Suppliers and Price of N-(1-methylpiperidin-4-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(1-methylpiperidin-4-yl)benzamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:218.141913202
Heavy Atom Count:16
Complexity:228

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)NC(=O)C2=CC=CC=C2

Technology Process of N-(1-methylpiperidin-4-yl)benzamide

There total 8 articles about N-(1-methylpiperidin-4-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 41838-46-4
4-Amino-1-methylpiperidine

: 98-88-4
benzoyl chloride

: 1141-58-8
N-(1-methyl-[4]piperidyl)-benzamide

Guidance literature:: In benzene; Ambient temperature;
DOI:10.1016/S0014-827X(98)00016-0

Reference yield: 60.0%

: 127722-77-4
N-(1-methyl-1,2,5,6-tetrahydro-4-pyridinyl) benzamide

: 1141-58-8
N-(1-methyl-[4]piperidyl)-benzamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1016/0223-5234(90)90159-Z

Reference yield:

: 504-24-5
4-aminopyridine

: 1141-58-8
N-(1-methyl-[4]piperidyl)-benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 73 percent / triethylamine / 1,2-dichloro-ethane / 3 h / 60 °C

2: 96 percent / acetonitrile / 1 h / Heating

3: 78 percent / NaBH₄ / methanol / 3 h / Heating

4: 60 percent / H₂ / 10percent Pd/C / ethanol

With sodium tetrahydroborate; hydrogen; triethylamine; palladium on activated charcoal; In methanol; ethanol; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/0223-5234(90)90159-Z