2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran

Base Information

Chemical Name:2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran
CAS No.:114212-23-6
Molecular Formula:C12H15BrO2
Molecular Weight:271.154
Hs Code.:
DSSTox Substance ID:DTXSID50551476

Synonyms:114212-23-6;2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran;2-(2-BROMO-4-METHYLPHENOXY)OXANE;2H-pyran, 2-(2-bromo-4-methylphenoxy)tetrahydro-;SCHEMBL1423552;DTXSID50551476;RMPVKDAXBCLEHT-UHFFFAOYSA-N;AKOS022173165;2-(2-bromo-4-methyl-phenoxy)-tetrahydropyran

Suppliers and Price of 2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:270.02554
Heavy Atom Count:15
Complexity:198

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)OC2CCCCO2)Br

Technology Process of 2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran

There total 2 articles about 2-(2-bromo-4-methylphenoxy)tetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.8%

: 114212-23-6
2-(2-bromo-4-methylphenoxy)-tetrahydro-2H-pyran

Guidance literature:: With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃; for 8h; Inert atmosphere;

Reference yield: 87.5%

: 110-87-2
3,4-dihydro-2H-pyran

: 6627-55-0
2-bromo-p-cresol

: 114212-23-6
2-(2-bromo-4-methylphenoxy)-tetrahydro-2H-pyran

Guidance literature:: With pyridinium p-toluenesulfonate; In 1,1,2,2-tetrachloroethane; at 60 ℃; for 6h; Inert atmosphere;

Reference yield: 35.0%

: 938083-09-1
3,3'-[oxybis(methylene)]bis(bromobenzene)

: 114212-23-6
2-(2-bromo-4-methylphenoxy)-tetrahydro-2H-pyran

: 1312236-76-2
2,2'-[(oxybis(methylene))bis(5-methyl-[1,1'-biphenyl]-3',2-diyl)]bis(oxy)bis(tetrahydro-2H-pyran)

Guidance literature:: 2-(2-bromo-4-methylphenoxy)-tetrahydro-2H-pyran; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

With zinc(II) chloride; In tetrahydrofuran; hexane; for 1h;

3,3'-[oxybis(methylene)]bis(bromobenzene); With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; hexane; for 2h; Reflux;
DOI:10.1021/ja2021312