Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 3,5-hexadienyl ester, (E)-

Base Information

• Chemical Name: Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 3,5-hexadienyl ester, (E)-
• CAS No.: 114250-96-3
• Molecular Formula: C16H18O3S
• Molecular Weight: 290.383
• Mol file: 114250-96-3.mol

Synonyms:

Chemical Property of Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 3,5-hexadienyl ester, (E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 3,5-hexadienyl ester, (E)-

There total 2 articles about Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 3,5-hexadienyl ester, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E)-hexa-3,5-dien-1-ol (73670-87-8) + 2-((2-oxo-2-phenylethyl)thio)acetic acid (22536-46-5) → (E)-3,5-hexadienyl (phenacylthio)acetate (114250-96-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; diethyl ether; Ambient temperature;

DOI:10.1021/jo00245a018

Reference yield:

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → (E)-3,5-hexadienyl (phenacylthio)acetate (114250-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / triethylamine / tetrahydrofuran / 1.5 h / 5 - 20 °C

2: 91 percent / dicyclohexylcarbodiimide (DCC), 4-(N,N-dimethylamino)pyridine (DMAP) / diethyl ether; tetrahydrofuran / Ambient temperature

With dmap; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; diethyl ether;

DOI:10.1021/jo00245a018

upstream raw materials:

(E)-hexa-3,5-dien-1-ol

2-((2-oxo-2-phenylethyl)thio)acetic acid

1-chloroacetophenone