2-Chloroacetophenone

Base Information Edit

Chemical Name:2-Chloroacetophenone
CAS No.:532-27-4
Molecular Formula:C8H7ClO
Molecular Weight:154.596
Hs Code.:2914700090
European Community (EC) Number:208-531-1,639-652-1
ICSC Number:0128
NSC Number:41666
UN Number:1697
UNII:88B5039IQG
DSSTox Substance ID:DTXSID9020293
Nikkaji Number:J2.629H
Wikipedia:Phenacyl_chloride
Wikidata:Q284209
NCI Thesaurus Code:C107326,C73902
Pharos Ligand ID:3L54FARDFBLA
ChEMBL ID:CHEMBL105712
Mol file:532-27-4.mol

Synonyms:2 Chloro 1 phenylethanone;2 Chloroacetophenone;2-Chloro-1-phenylethanone;2-Chloroacetophenone;3' Chloroacetophenone;3'-Chloroacetophenone;alpha Chloroacetophenone;alpha-Chloroacetophenone;Chloracetophenone;Chloroacetophenone;Mace;omega Chloroacetophenone;omega-Chloroacetophenone

Suppliers and Price of 2-Chloroacetophenone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Chloroacetophenone Edit

Chemical Property:

Appearance/Colour:White to light yellow crystal
Melting Point:54-56 °C
Refractive Index:1.5438
Boiling Point:244.5 °C at 760 mmHg
Flash Point:104.8 °C
PSA：17.07000
Density:1.168 g/cm³
LogP:2.10810
Water Solubility.:insoluble. <0.1 g/100 mL at 19℃
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:154.0185425
Heavy Atom Count:10
Complexity:116
Transport DOT Label:Poison

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s): T
Hazard Codes: T:Toxic;
Statements: R23/25:; R36/37/38:;
Safety Statements: S26:; S28A:; S36/37/39:; S45:;

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Toxic Gases & Vapors -> Tear Gas Agents
Canonical SMILES:C1=CC=C(C=C1)C(=O)CCl
Inhalation Risk:A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20 °C.
Effects of Short Term Exposure:Lachrymation. The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract. Inhalation of the vapour or aerosol may cause lung oedema. The effects may be delayed. Medical observation is indicated.
Effects of Long Term Exposure:Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization.

Technology Process of 2-Chloroacetophenone

There total 185 articles about 2-Chloroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 98-86-2
acetophenone

: 2648-61-5
2,2-dichloroacetophenone

: 532-27-4,108321-66-0,164322-25-2
1-chloroacetophenone

Guidance literature:: With hydrogenchloride; dihydrogen peroxide; In ethanol; at 91 - 93 ℃; for 0.25h; Further Variations:; Solvents; Temperatures; time; Product distribution;
DOI:10.1055/s-2004-834871