1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Base Information

Chemical Name:1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide
CAS No.:114261-04-0
Molecular Formula:C₁₄H₁₆N₂O
Molecular Weight:228.294
Hs Code.:
DSSTox Substance ID:DTXSID80530138
Nikkaji Number:J1.622.974A
Wikidata:Q82401084
Mol file:114261-04-0.mol

Synonyms:114261-04-0;1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide;DTXSID80530138

Suppliers and Price of 1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:228.126263138
Heavy Atom Count:17
Complexity:351

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C=C(C1)C(=O)N)CC2=CC=CC=C2

Technology Process of 1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

There total 7 articles about 1-Benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-benzyl-3-carbamoyl-5-methyl-pyridin-1-ium bromide

: 114261-04-0
1-benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Guidance literature:: With sodium dithionite; sodium hydrogencarbonate; In water; at 20 ℃; for 3h; Darkness; Inert atmosphere;
DOI:10.1002/adsc.202100726

Reference yield:

: 591-22-0
3,5-Lutidine

: 114261-04-0
1-benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: KMnO₄ / acetone; H₂O / 2 h / 70 °C

2: Heating

3: 74 percent / saturated aq. NH₃ / 24 h / Ambient temperature

4: acetonitrile

5: Na₂S₂O₄

With ammonium hydroxide; potassium permanganate; sodium dithionite; In water; acetone; acetonitrile;

Reference yield:

: 3222-49-9
5-methylnicotinic acid

: 114261-04-0
1-benzyl-5-methyl-1,4-dihydropyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: Heating

2: 74 percent / saturated aq. NH₃ / 24 h / Ambient temperature

3: acetonitrile

4: Na₂S₂O₄

With ammonium hydroxide; sodium dithionite; In acetonitrile;