Ethyl 5-nitrobenzofuran-2-carboxylate

Base Information Edit

Chemical Name:Ethyl 5-nitrobenzofuran-2-carboxylate
CAS No.:69604-00-8
Molecular Formula:C11H9NO5
Molecular Weight:235.196
Hs Code.:29329990
European Community (EC) Number:614-989-7,672-147-4
UNII:BWP4ZD8WZF
DSSTox Substance ID:DTXSID50989694
Wikidata:Q72476337
Mol file:69604-00-8.mol

Synonyms:Ethyl 5-nitrobenzofuran-2-carboxylate;69604-00-8;69404-00-8;ethyl 5-nitro-1-benzofuran-2-carboxylate;2-Benzofurancarboxylic acid, 5-nitro-, ethyl ester;Ethyl 5-nitrobenzo[b]furan-2-carboxylate;BWP4ZD8WZF;5-Nitrobenzofuran-2-carboxylic acid ethyl ester;5-NITROBENZO[B]FURAN-2-CARBOXYLIC ACID ETHYL ESTER;MFCD00275272;ethyl 5-nitrobenzo[d]furan-2-carboxylate;UNII-BWP4ZD8WZF;SCHEMBL2249264;DTXSID50989694;AMY21658;BCP08877;CS-M1104;GEO-01364;AKOS005071959;BB-0814;AC-26406;ethyl-5-nitro-1-benzofuran-2-carboxylate;SY024789;E0950;Ethyl 5-nitrobenzofuran-2-carboxylate, 97%;FT-0620704;FT-0680847;2-Benzofurancarboxylicacid,5-nitro-,ethyl ester;I11522;5-Nitro-benzofuran-2-carboxylic acid ethyl ester;A836478;A866800;J-521153;J-640084;J-800067;W-200484

Suppliers and Price of Ethyl 5-nitrobenzofuran-2-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Nitrobenzofuran-2-carboxylic acid ethyl ester
5g
$ 433.00

Usbiological
5-Nitrobenzofuran-2-carboxylic acid ethyl ester
25g
$ 619.00

TRC
Ethyl 5-nitrobenzofuran-2-carboxylate
5g
$ 140.00

TCI Chemical
Ethyl 5-Nitrobenzofuran-2-carboxylate >97.0%(GC)
25g
$ 158.00

TCI Chemical
Ethyl 5-Nitrobenzofuran-2-carboxylate >97.0%(GC)
5g
$ 32.00

SynQuest Laboratories
Ethyl 5-nitrobenzo[b]furan-2-carboxylate
1 g
$ 16.00

Sigma-Aldrich
Ethyl 5-nitrobenzofuran-2-carboxylate 97%
5g
$ 126.00

Frontier Specialty Chemicals
Ethyl 5-nitrobenzofuran-2-carboxylate 97%
1g
$ 16.00

Crysdot
Ethyl 5-nitrobenzofuran-2-carboxylate 95+%
100g
$ 444.00

ChemScene
Ethyl 5-nitrobenzofuran-2-carboxylate 99.94%
100g
$ 239.00

Total 106 raw suppliers

Chemical Property of Ethyl 5-nitrobenzofuran-2-carboxylate Edit

Chemical Property:

Appearance/Colour:Light yellow to light brown powder
Vapor Pressure:2.34E-05mmHg at 25°C
Melting Point:150 °C
Refractive Index:1.603
Boiling Point:359.7 °C at 760 mmHg
Flash Point:171.3 °C
PSA：85.26000
Density:1.362 g/cm³
LogP:3.04090
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:slightly sol. in Acetone
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:235.04807239
Heavy Atom Count:17
Complexity:314

Purity/Quality:

98% ^*data from raw suppliers

5-Nitrobenzofuran-2-carboxylic acid ethyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(O1)C=CC(=C2)[N+](=O)[O-]
Uses Deriatives of benzofuran-2-carboxylic acid are known for exhibiting various pharmacological activities such as selective adenosine A2A receptor antagonists, anti-inflammatory agents and local anaesthe tics. Benzofuran-2-carboxylic acids bearing benzoyl nitrogen such as Ethyl 5-Nitrobenzofuran-2-carboxylate, are used as DNA-binding groups, where the these structural subunits mimic natural antitumor agents such as duocarmycin and netropsin.

Technology Process of Ethyl 5-nitrobenzofuran-2-carboxylate

There total 15 articles about Ethyl 5-nitrobenzofuran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.2%