Benzyl (2-oxoazetidin-1-yl)acetate

Base Information

Chemical Name:Benzyl (2-oxoazetidin-1-yl)acetate
CAS No.:114342-03-9
Molecular Formula:C12H13NO3
Molecular Weight:219.24
Hs Code.:
DSSTox Substance ID:DTXSID20551948
Wikidata:Q82431867

Synonyms:114342-03-9;Benzyl (2-oxoazetidin-1-yl)acetate;SCHEMBL9708647;DTXSID20551948

Suppliers and Price of Benzyl (2-oxoazetidin-1-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzyl (2-oxoazetidin-1-yl)acetate

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:219.08954328
Heavy Atom Count:16
Complexity:271

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C1=O)CC(=O)OCC2=CC=CC=C2

Technology Process of Benzyl (2-oxoazetidin-1-yl)acetate

There total 3 articles about Benzyl (2-oxoazetidin-1-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 130676-99-2
benzyl (3-bromopropionamido)acetate

: 114342-03-9
benzyl (2-oxo-azetidin-1-yl)acetate

Guidance literature:: With potassium hydroxide; tetrabutylammomium bromide; In dichloromethane; acetonitrile; for 4.5h;
DOI:10.1016/j.bmcl.2007.06.089

Reference yield: 36.0%

: 135727-36-5
benzyl 3-iodopropionamidoacetate

: 114342-03-9
benzyl (2-oxo-azetidin-1-yl)acetate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at -10 ℃; for 3h;
DOI:10.1016/S0040-4020(01)86446-2

Reference yield:

: 1738-76-7
glycine benzyl ester p-toluenesulfonic acid salt

: 114342-03-9
benzyl (2-oxo-azetidin-1-yl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / aq. sodium hydroxide (pH 5.5 - 6.5) / tetrahydrofuran; H₂O / 0.75 h / 4 °C

2: 38 percent / potassium hydroxide, tetrabutylammonium bromide / CH₂Cl₂; acetonitrile / 0.5 h

With potassium hydroxide; sodium hydroxide; tetrabutylammomium bromide; In tetrahydrofuran; dichloromethane; water; acetonitrile;
DOI:10.1039/P19900001513