130676-99-2

Upstream product

• 1738-76-7 glycine benzyl ester p-toluenesulfonic acid salt 
• 15486-96-1 3-Bromopropionyl chloride 
• 120926-60-5 glycine benzyl ester trifluoroacetic salt 

Downstream Products

• 114342-03-9 benzyl (2-oxo-azetidin-1-yl)acetate 
• 135727-36-5 benzyl 3-iodopropionamidoacetate 
• 135727-39-8 C₂₃H₂₅⁽²⁾HN₂O₆ 
• 130677-11-1 (2S,3R)-4-nitrobenzyl 5-(4-bromophenylsulphonylamino)-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 130677-11-1 threo-4-nitrobenzyl 5-(4-bromophenylsulphonylamino)-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 114342-11-9 threo-benzyl-N⁵-benzyloxycarbonylamino-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 114342-11-9 erythro-benzyl 5-benzyloxycarbonylamino-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 130793-34-9 (2S,3R)-4-bromobenzyl 5-azido-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 130793-33-8 (2S,3R)-benzyl 5-azido-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 112240-59-2 proclavaminic acid 
• 112240-59-2 threo-5-amino-3-hydroxy-2-(2-oxoazetidin-1-yl)valeric acid 
• 112240-59-2 erythro-5-amino-3-hydroxy-2-(2-oxoazetidin-1-yl)valeric acid 
• 130677-10-0 (2S,3R)-4-bromobenzyl 5-(4,5-bismethoxycarbonyl-1,2,3-triazol-1-yl)-3-hydroxy-2-(2-oxoazetidin-1-yl)valerate 
• 130677-02-0 benzyl 3-hydroxy-2-(2-oxoazetidin-1-yl)-5-phthalimidovalerate 

Relevant academic research and scientific papers

A minimalistic approach to identify substrate binding features in B1 Metallo-β-lactamases

The 2-oxoazetidinylacetate sodium salt was synthesized as a model of a minimal β-lactam drug. This compound and the monobactam aztreonam were assayed as substrates of the Metallo-β-lactamase BcII. None of them was hydrolyzed by the enzyme. While the azeti

Studies on the Biosynthesis of Clavulanic Acid. Part 4. Synthetic Routes to the Monocyclic β-Lactam Precursor, Proclavaminic Acid

Aldol condensation of 3-substituted propionaldehydes with the lithium enolate of ethyl or benzyl(2-oxoazetidin-1-yl)acetate yielded derivatives of proclavaminic acid.The proportion of the threo diastereoisomer in the aldol product could be increased by th