Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-
CAS No.:114443-34-4
Molecular Formula:C₁₄H₁₀F₃NO
Molecular Weight:265.235
Hs Code.:
DSSTox Substance ID:DTXSID80572033
Wikidata:Q82460261
Mol file:114443-34-4.mol

Synonyms:114443-34-4;Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-;SCHEMBL5921849;DTXSID80572033;AKOS011394159;Pyridin-4-yl-2-(4-trifluoromethyl-phenyl)-ethanone;1-(Pyridin-4-yl)-2-[4-(trifluoromethyl)phenyl]ethan-1-one

Suppliers and Price of Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:265.07144843
Heavy Atom Count:19
Complexity:302

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(=O)C2=CC=NC=C2)C(F)(F)F

Technology Process of Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-

There total 3 articles about Ethanone, 1-(4-pyridinyl)-2-[4-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 114443-87-7
Phenyl-[(Z)-1-pyridin-4-yl-2-(4-trifluoromethyl-phenyl)-vinyl]-amine

: 114443-34-4
1-Pyridin-4-yl-2-(4-trifluoromethyl-phenyl)-ethanone

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; isopropyl alcohol; for 2h; Yield given; Ambient temperature;
DOI:10.1016/S0040-4039(98)00140-3

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 114443-34-4
1-Pyridin-4-yl-2-(4-trifluoromethyl-phenyl)-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / propan-2-ol; various solvent(s) / 4 h / Ambient temperature

2: anh. Cs₂CO₃ / tetrahydrofuran; propan-2-ol / 16 h / Ambient temperature

3: 3N HCl / H₂O; tetrahydrofuran; propan-2-ol / 2 h / Ambient temperature

With hydrogenchloride; caesium carbonate; In tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1016/S0040-4039(98)00140-3

Reference yield:

: 3360-72-3
(anilino-pyridin-4-yl-methyl)-phosphonic acid diphenyl ester

: 114443-34-4
1-Pyridin-4-yl-2-(4-trifluoromethyl-phenyl)-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: anh. Cs₂CO₃ / tetrahydrofuran; propan-2-ol / 16 h / Ambient temperature

2: 3N HCl / H₂O; tetrahydrofuran; propan-2-ol / 2 h / Ambient temperature

With hydrogenchloride; caesium carbonate; In tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1016/S0040-4039(98)00140-3