3360-72-3Relevant academic research and scientific papers
Heteroaromatic quinoline compounds
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Page/Page column 30, (2008/06/13)
The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS
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Page/Page column 90-91, (2008/06/13)
The present invention provides compounds of formula (I): a stereoisomer or a pharmaceutically acceptable salt thereof, wherein the variables R1, R2, R3, R4, X and n are defined as defined herein. Additionally, a
An improved and practical procedure for the synthesis of substituted phenylacetylpyridines
Journet, Michel,Cai, Dongwei,Larsen, Robert D.,Reider, Paul J.
, p. 1717 - 1720 (2007/10/03)
A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.
