alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid

Base Information

Chemical Name:alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid
CAS No.:78868-43-6
Molecular Formula:C₁₈H₁₅NO₃
Molecular Weight:293.322
Hs Code.:
DSSTox Substance ID:DTXSID701000096

Synonyms:BRN 4502722;alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid;Benzeneacetic acid, alpha-methyl-4-(5-phenyl-3-isoxazolyl)-;78868-43-6;2-[4-(5-phenyl-1,2-oxazol-3-yl)phenyl]propanoic acid;DTXSID701000096;LS-28949

Suppliers and Price of alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid

Chemical Property:

Vapor Pressure:4.16E-11mmHg at 25°C
Boiling Point:507.1°Cat760mmHg
Flash Point:260.5°C
Density:1.218g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:293.10519334
Heavy Atom Count:22
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)C2=NOC(=C2)C3=CC=CC=C3)C(=O)O

Technology Process of alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid

There total 4 articles about alpha-Methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 78868-35-6
2-[4-(2,3-Dibromo-3-phenyl-propionyl)-phenyl]-propionic acid

: 78868-43-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; In methanol;

Reference yield:

: 41387-29-5
2-[4-(acetyl)phenyl] propanoic acid

: 78868-43-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 30 percent / 40percent aq. NaOH / ethanol

2: 80 percent / bromine / diethyl ether

3: 60 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol

With sodium hydroxide; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether; ethanol;

Reference yield:

: 78874-47-2
2-{4-[(E)-(3-Phenyl-acryloyl)]-phenyl}-propionic acid

: 78868-43-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / bromine / diethyl ether

2: 60 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol

With sodium hydroxide; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether;