Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate

Base Information

Chemical Name:Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate
CAS No.:78868-51-6
Molecular Formula:C₁₉H₁₇NO₃
Molecular Weight:307.349
Hs Code.:
DSSTox Substance ID:DTXSID001000102

Synonyms:BRN 4520931;78868-51-6;Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate;Benzeneacetic acid, alpha-methyl-4-(5-phenyl-3-isoxazolyl)-, methyl ester;methyl 2-[4-(5-phenyl-1,2-oxazol-3-yl)phenyl]propanoate;DTXSID001000102;LS-28950

Suppliers and Price of Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate

Chemical Property:

Vapor Pressure:1.05E-08mmHg at 25°C
Boiling Point:461.6°Cat760mmHg
Flash Point:233°C
Density:1.155g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:307.12084340
Heavy Atom Count:23
Complexity:386

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)C2=NOC(=C2)C3=CC=CC=C3)C(=O)OC

Technology Process of Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate

There total 5 articles about Methyl alpha-methyl-4-(5-phenyl-3-isoxazolyl)benzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 67-56-1
methanol

: 78868-43-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid

: 78868-51-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid methyl ester

Guidance literature:: With sulfuric acid;

Reference yield:

: 41387-29-5
2-[4-(acetyl)phenyl] propanoic acid

: 78868-51-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 30 percent / 40percent aq. NaOH / ethanol

2: 80 percent / bromine / diethyl ether

3: 60 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol

4: 80 percent / conc. H₂SO₄

With sodium hydroxide; sulfuric acid; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether; ethanol;

Reference yield:

: 78874-47-2
2-{4-[(E)-(3-Phenyl-acryloyl)]-phenyl}-propionic acid

: 78868-51-6
2-[4-(5-Phenyl-isoxazol-3-yl)-phenyl]-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / bromine / diethyl ether

2: 60 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol

3: 80 percent / conc. H₂SO₄

With sodium hydroxide; sulfuric acid; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether;