1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil

Base Information

Chemical Name:1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil
CAS No.:87782-49-8
Molecular Formula:C₁₁H₁₃FN₂O₅
Molecular Weight:272.233
Hs Code.:
Mol file:87782-49-8.mol

Synonyms:1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethenyl-

Suppliers and Price of 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil

Chemical Property:

PKA:9.07±0.10(Predicted)
PSA：104.55000
Density:1.52 g/cm³
LogP:-1.23170

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil

There total 5 articles about 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 87782-45-4
1-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil

: 87782-49-8
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil

Guidance literature:: With ammonia; In methanol; for 24h; Ambient temperature;
DOI:10.1021/jm00367a020

Reference yield:

: 56632-81-6
1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide

: 87782-49-8
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / CH₂Cl₂ / 168 h / Ambient temperature

2: 58 percent / NH₃ / methanol / 24 h / Ambient temperature

With ammonia; In methanol; dichloromethane;
DOI:10.1021/jm00367a020

Reference yield:

: 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose

: 87782-49-8
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil

Guidance literature:: Multi-step reaction with 3 steps

1: HBr / CH₂Cl₂ / 4 °C

2: 43 percent / CH₂Cl₂ / 168 h / Ambient temperature

3: 58 percent / NH₃ / methanol / 24 h / Ambient temperature

With ammonia; hydrogen bromide; In methanol; dichloromethane;
DOI:10.1021/jm00367a020