4',5'-Dimethylfluorescein

Base Information

Chemical Name:4',5'-Dimethylfluorescein
CAS No.:118797-71-0
Molecular Formula:C22H16O5
Molecular Weight:360.366
Hs Code.:
DSSTox Substance ID:DTXSID10152241
Wikidata:Q83018869
Mol file:118797-71-0.mol

Synonyms:4',5'-dimethylfluorescein

Suppliers and Price of 4',5'-Dimethylfluorescein

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 19 raw suppliers

Chemical Property of 4',5'-Dimethylfluorescein

Chemical Property:

Boiling Point:607.5 °C at 760 mmHg
Flash Point:220.8 °C
PSA：75.99000
Density:1.5 g/cm³
LogP:4.28260
XLogP3:4.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:360.09977361
Heavy Atom Count:27
Complexity:576

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC2=C1OC3=C(C24C5=CC=CC=C5C(=O)O4)C=CC(=C3C)O)O

Technology Process of 4',5'-Dimethylfluorescein

There total 1 articles about 4',5'-Dimethylfluorescein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 85-44-9
phthalic anhydride

: 608-25-3
2-methylbenzene-1,3-diol

: 118797-71-0
3′,6′?dihydroxy?4′,5′?dimethyl?3H?spiro[2?benzofuran?1,9′?xanthen]?3?one

Guidance literature:: With Zn_0.95*Ti_0.05O; In neat (no solvent); at 160 ℃; for 1.5h; Green chemistry;
DOI:10.1016/j.catcom.2018.11.008

Reference yield:

: 118797-71-0
3′,6′?dihydroxy?4′,5′?dimethyl?3H?spiro[2?benzofuran?1,9′?xanthen]?3?one

: 357615-02-2
4',5'-bis(bromomethyl)fluoresceine dibenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 2.5 h / 140 °C

2: 98.2 percent / 1,3-dibromo-5,5-dimethylhydantoin; 1,1'-azobis(cyclohexanecarbonitrile); AcOH / chlorobenzene / 72 h / 40 °C

With pyridine; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; acetic acid; 1,1'-azobis(1-cyanocyclohexanenitrile); In chlorobenzene;
DOI:10.1021/ja010059l

Reference yield:

: 118797-71-0
3′,6′?dihydroxy?4′,5′?dimethyl?3H?spiro[2?benzofuran?1,9′?xanthen]?3?one

: 9-(o-carboxyphenyl)-4,5-bis[bis(2-pyridylmethyl)aminomethyl]-6-hydroxy-3-xanthanone

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 2.5 h / 140 °C

2: 98.2 percent / 1,3-dibromo-5,5-dimethylhydantoin; 1,1'-azobis(cyclohexanecarbonitrile); AcOH / chlorobenzene / 72 h / 40 °C

3: 36.7 percent / DMSO; NaHCO₃ / 4 h / 150 °C

4: 27.8 percent / sodium triacetoxyborohydride; AcOH / 1,2-dichloro-ethane / 12 h / 20 °C

With pyridine; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; acetic acid; dimethyl sulfoxide; 1,1'-azobis(1-cyanocyclohexanenitrile); In 1,2-dichloro-ethane; chlorobenzene;
DOI:10.1021/ja010059l