357615-02-2

Basic information

• Product Name: 4',5'-bis(bromomethyl)fluoresceine dibenzoate
• Synonyms: 4',5'-bis(bromomethyl)fluoresceine dibenzoate
• CAS NO: 357615-02-2
• Molecular Weight: 726.374
• Mol File: 357615-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4',5'-bis(bromomethyl)fluoresceine dibenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4',5'-bis(bromomethyl)fluoresceine dibenzoate(357615-02-2)
• EPA Substance Registry System: 4',5'-bis(bromomethyl)fluoresceine dibenzoate(357615-02-2)

Safety Data

• Hazardous Substances Data: 357615-02-2(Hazardous Substances Data)

Upstream product

• 118797-71-0 3′,6′?dihydroxy?4′,5′?dimethyl?3H?spiro[2?benzofuran?1,9′?xanthen]?3?one 
• 608-25-3 2-methylbenzene-1,3-diol 
• 85-44-9 phthalic anhydride 
• 357615-01-1 4',5'-dimethylfluorescein dibenzoate 

Downstream Products

• 1344032-74-1 4',5'-bis(hydroxymethyl)fluorescein dibenzoate 
• 1344032-84-3 C₆₄H₆₀O₂₇ 
• 1344032-83-2 C₅₈H₅₂O₂₃ 

Relevant articles and documents

Fluorescent sensors for Zn2+ based on a fluorescein platform: Synthesis, properties and intracellular distribution

Two new fluorescent sensors for Zn2+ that utilize fluorescein as a reporting group, Zinpyr-1 and Zinpyr-2, have been synthesized and characterized. Zinpyr-1 is prepared in one step via a Mannich reaction, and Zinpyr-2 is obtained in a multistep synthesis that utilizes 4′,5′-fluorescein dicarboxaldehyde as a key intermediate. Both Zinpyr sensors have excitation and emission wavelengths in the visible range (～500 nm), dissociation constants (Kd1) for Zn2+ of 2+ cation to the sensor, which inhibits a photoinduced electron transfer (PET) quenching pathway. The X-ray crystal structure of a 2:1 Zn2+:Zinpyr-1 complex has also been solved, and is the first structurally characterized example of a complex of fluorescein substituted with metal binding ligands.