3,4,5-Trihydroxybenzamidoxime

Base Information

Chemical Name:3,4,5-Trihydroxybenzamidoxime
CAS No.:95933-74-7
Molecular Formula:C₇H₈N₂O₄
Molecular Weight:184.152
Hs Code.:
Nikkaji Number:J535.319J
Wikidata:Q27166360
Mol file:95933-74-7.mol

Synonyms:N',3,4,5-tetrahydroxybenzene-1-carboximidamide;N,3,4,5-tetrahydroxybenzene-1-carboximidamide;Q27166360;4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxy-1-cyclohexa-2,5-dienone

Suppliers and Price of 3,4,5-Trihydroxybenzamidoxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Trimidox
10mg
$ 145.00

Cayman Chemical
Trimidox ≥98%
10mg
$ 93.00

Cayman Chemical
Trimidox ≥98%
5mg
$ 49.00

Cayman Chemical
Trimidox ≥98%
50mg
$ 392.00

Cayman Chemical
Trimidox ≥98%
100mg
$ 686.00

ApexBio Technology
Trimidox
100mg
$ 950.00

ApexBio Technology
Trimidox
50mg
$ 543.00

AK Scientific
Trimidox
5mg
$ 166.00

Total 7 raw suppliers

Chemical Property of 3,4,5-Trihydroxybenzamidoxime

Chemical Property:

Vapor Pressure:0.00361mmHg at 25°C
Boiling Point:249.7°Cat760mmHg
Flash Point:104.8°C
PSA：116.80000
Density:1.872g/cm³
LogP:0.59820
Solubility.:≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
XLogP3:0.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:184.04840674
Heavy Atom Count:13
Complexity:197

Purity/Quality:

≥98% ^*data from raw suppliers

Trimidox ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1O)O)O)C(=NO)N
Description Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in HL-60 cells, inducing apoptosis via activation of caspases without altering the cell cycle distribution. Trimidox inhibits growth of human promyelocytic leukemia HL-60 cells with an IC50 value of 35 μM.
Uses Trimidox is a specific ribonucleotide reductase inhibitor.

Technology Process of 3,4,5-Trihydroxybenzamidoxime

There total 1 articles about 3,4,5-Trihydroxybenzamidoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: