[3-(Aminomethyl)phenoxy]acetic acid

Base Information

Chemical Name:[3-(Aminomethyl)phenoxy]acetic acid
CAS No.:115464-36-3
Molecular Formula:C9H11NO3
Molecular Weight:181.191
Hs Code.:
DSSTox Substance ID:DTXSID80568234

Synonyms:115464-36-3;2-(3-(aminomethyl)phenoxy)acetic acid;2-[3-(aminomethyl)phenoxy]acetic acid;[3-(Aminomethyl)phenoxy]acetic acid;SCHEMBL2936246;DTXSID80568234;AKOS010514966;CS-0346318;EN300-150722

Suppliers and Price of [3-(Aminomethyl)phenoxy]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [3-(Aminomethyl)phenoxy]acetic acid

Chemical Property:

XLogP3:-2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:181.07389321
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OCC(=O)O)CN

Technology Process of [3-(Aminomethyl)phenoxy]acetic acid

There total 4 articles about [3-(Aminomethyl)phenoxy]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1879-58-9
2-(3-cyanophenoxy) acetic acid

: 115464-36-3
<3-(aminomethyl)phenoxy>acetic acid

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; acetic acid; at 20 ℃; for 4h;
DOI:10.1021/acs.jmedchem.9b00723

Reference yield:

: 873-62-1
m-cyanophenol

: 115464-36-3
<3-(aminomethyl)phenoxy>acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 2 h / Reflux

2: lithium hydroxide / water; tetrahydrofuran / 1 h / 20 °C

3: 5%-palladium/activated carbon; hydrogen / methanol; acetic acid / 4 h / 20 °C

With 5%-palladium/activated carbon; hydrogen; potassium carbonate; lithium hydroxide; In tetrahydrofuran; methanol; water; acetic acid; acetone;
DOI:10.1021/acs.jmedchem.9b00723

Reference yield:

: 55197-25-6
ethyl [(3-cyanophenyl)oxy]acetate

: 115464-36-3
<3-(aminomethyl)phenoxy>acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide / water; tetrahydrofuran / 1 h / 20 °C

2: 5%-palladium/activated carbon; hydrogen / methanol; acetic acid / 4 h / 20 °C

With 5%-palladium/activated carbon; hydrogen; lithium hydroxide; In tetrahydrofuran; methanol; water; acetic acid;
DOI:10.1021/acs.jmedchem.9b00723