N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide

Base Information

Chemical Name:N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide
CAS No.:115514-67-5
Molecular Formula:C16H16ClNO2
Molecular Weight:289.762
Hs Code.:
DSSTox Substance ID:DTXSID20557268
Wikidata:Q82439125
Mol file:115514-67-5.mol

Synonyms:115514-67-5;N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide;DTXSID20557268;AKOS016035351

Suppliers and Price of N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:289.0869564
Heavy Atom Count:20
Complexity:305

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCNC(=O)C2=CC=CC=C2)Cl

Technology Process of N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide

There total 3 articles about N-[2-(3-Chloro-4-methoxyphenyl)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 7569-87-1
3-chloro-4-methoxyphenethylamine

: 98-88-4
benzoyl chloride

: 115514-67-5
N-benzoyl-3-chloro-4-methoxyphenethylamine

Guidance literature:: With sodium hydroxide; In diethyl ether; Ambient temperature;
DOI:10.1021/jm00118a012

Reference yield:

: 104-47-2
p-methoxybenzylnitrile

: 115514-67-5
N-benzoyl-3-chloro-4-methoxyphenethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Cl₂ / acetic acid / 0.5 h / Ambient temperature

2: 35 percent / LiAlH₄ / tetrahydrofuran / 5 h / Heating

3: 67 percent / 20percent NaOH / diethyl ether / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; chlorine; In tetrahydrofuran; diethyl ether; acetic acid;
DOI:10.1021/jm00118a012

Reference yield:

: 7569-58-6
2-(3-chloro-4-methoxyphenyl)acetonitrile

: 115514-67-5
N-benzoyl-3-chloro-4-methoxyphenethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / LiAlH₄ / tetrahydrofuran / 5 h / Heating

2: 67 percent / 20percent NaOH / diethyl ether / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00118a012