Propanedioic acid, 3-cyclohexen-1-yl-, dimethyl ester

Base Information

• Chemical Name: Propanedioic acid, 3-cyclohexen-1-yl-, dimethyl ester
• CAS No.: 115740-69-7
• Molecular Formula: C11H16O4
• Molecular Weight: 212.246
• Mol file: 115740-69-7.mol

Synonyms:

Chemical Property of Propanedioic acid, 3-cyclohexen-1-yl-, dimethyl ester

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanedioic acid, 3-cyclohexen-1-yl-, dimethyl ester

There total 3 articles about Propanedioic acid, 3-cyclohexen-1-yl-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

Co(CO)3(C6H8)CH(COOCH3)2 (122471-29-8) → dimethyl 2-(cyclohex-2-en-1-yl)malonate (34939-28-1) + 4-cyclohexene (115740-69-7)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; enolate adduct in THF poured into 1.5 M HCl, stirred for 30 min at room temp., extd. with ether; washed with satd. NaCl, dried over MgSO4; removal of solvent; chromy. (silica gel, 30% Et2O/ petroleum ether);

Reference yield:

phenyliodoniomethanesulfonate (118163-37-4) + cyclohexene (110-83-8) → Tetramethyl ethylenetetracarboxylate (1733-15-9) + dimethyl 2-(cyclohex-2-en-1-yl)malonate (34939-28-1) + 4-cyclohexene (115740-69-7) + 2,2,5,5-tetraoxy-3,3,6,6-tetramethoxycarbonyl-1,4-dioxa-2,5-dithiane (109629-28-9)

Guidance literature:

In dichloromethane; at 20 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

bis(methoxycarbonyl)(phenyliodinio)methanide (145838-86-4) + cyclohexene (110-83-8) → dimethyl 2-(cyclohex-2-en-1-yl)malonate (34939-28-1) + 4-cyclohexene (115740-69-7)

Guidance literature:

With boron trifluoride diethyl etherate; lithium perchlorate; In ethyl acetate; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1007/BF00957274

upstream raw materials:

bis(methoxycarbonyl)(phenyliodinio)methanide

cyclohexene

phenyliodoniomethanesulfonate

Co(CO)3(C₆H₈)CH(COOCH₃)2