(1-Chloroethyl)(dimethyl)phenylsilane

Base Information

• Chemical Name: (1-Chloroethyl)(dimethyl)phenylsilane
• CAS No.: 17877-00-8
• Molecular Formula: C10H15ClSi
• Molecular Weight: 198.7646
• NSC Number: 96839
• DSSTox Substance ID: DTXSID50300385
• Mol file: 17877-00-8.mol

Synonyms:17877-00-8;(1-chloroethyl)(dimethyl)phenylsilane;NSC96839;NCIOpen2_001771;DTXSID50300385;NSC-96839

Chemical Property of (1-Chloroethyl)(dimethyl)phenylsilane

Chemical Property:

• Vapor Pressure: 0.0675mmHg at 25°C
• Boiling Point: 237.8°Cat760mmHg
• Flash Point: 100.5°C
• Density: 0.97g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 198.0631547
• Heavy Atom Count: 12
• Complexity: 139

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC([Si](C)(C)C1=CC=CC=C1)Cl

Technology Process of (1-Chloroethyl)(dimethyl)phenylsilane

There total 2 articles about (1-Chloroethyl)(dimethyl)phenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

chloromethyldimethylphenylsilane (1833-51-8) + methyl iodide (74-88-4) → rac-(1-chloroethyl)dimethylphenylsilane (17877-00-8)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; 1.) -78 deg C, 40 min, 2.) -40 deg C, 30 min;

DOI:10.1021/jo951931+

Reference yield:

→ rac-(1-chloroethyl)dimethylphenylsilane (17877-00-8)

Guidance literature:

<2-Chlor-aethyl>-dimethyl-phenyl-silan, 3M-Methylmagnesiumbromid, Siedetemp.;

DOI:10.1021/jm00334a035

Reference yield: 81.0%

rac-(1-chloroethyl)dimethylphenylsilane (17877-00-8) → rac-(1-iodoethyl)dimethylphenylsilane (17877-01-9)

Guidance literature:

With sodium iodide; In acetone; for 264h; Heating;

DOI:10.1016/0022-328X(91)83279-D

upstream raw materials:

chloromethyldimethylphenylsilane

methyl iodide

Downstream raw materials:

rac-(1-iodoethyl)dimethylphenylsilane

C₁₀H₁₅ClMgSi

Benzyl-[(1S,2R)-2-(dimethyl-phenyl-silanyl)-1-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-propyl]-amine

Benzyl-[(1S,2R)-2-(dimethyl-phenyl-silanyl)-1-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-propyl]-carbamic acid benzyl ester