Pentafluoropropionamide

Base Information

• Chemical Name: Pentafluoropropionamide
• CAS No.: 354-76-7
• Molecular Formula: C3H2F5NO
• Molecular Weight: 163.047
• Hs Code.: 2924199090
• European Community (EC) Number: 206-569-3
• DSSTox Substance ID: DTXSID0059871
• Nikkaji Number: J193.834G
• Wikidata: Q72499848
• Mol file: 354-76-7.mol

Synonyms:Pentafluoropropionamide;354-76-7;2,2,3,3,3-Pentafluoropropanamide;pentafluoropropanamide;Propanamide, 2,2,3,3,3-pentafluoro-;C3H2F5NO;2,2,3,3,3-Pentafluoropropionamide;EINECS 206-569-3;Perfluoropropanamide;Pentafluoropropionamide 97%;SCHEMBL808848;Pentafluoro propionic acid amide;DTXSID0059871;C3-H2-F5-N-O;AMY15415;MFCD00039771;AKOS003269747;2,2,3,3,3-Pentafluoropropanamide #;AS-60985;FT-0609055;P1316;EN300-39929;A822834;J-523894;Z406353702

Chemical Property of Pentafluoropropionamide

Chemical Property:

• Vapor Pressure: 2.79mmHg at 25°C
• Melting Point: 95 °C
• Refractive Index: 1.306
• Boiling Point: 157.2 °C at 760 mmHg
• Flash Point: 48.9 °C
• PSA: 43.09000
• Density: 1.535 g/cm³
• LogP: 1.36960
• Solubility.: Soluble in methanol.
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 163.00565450
• Heavy Atom Count: 10
• Complexity: 150

Purity/Quality:

98% ^*data from raw suppliers

Pentafluoropropionamide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(C(F)(F)F)(F)F)N
• Uses: 2,2,3,3,3-Pentafluoropropionamide, is used as a chemical, organic, pharamceutical intermediate.

Technology Process of Pentafluoropropionamide

There total 19 articles about Pentafluoropropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

perfluoropropanoyl fluoride (422-61-7) → 2,2,3,3,3-pentafluoropropionamide (354-76-7)

Guidance literature:

With ammonia; at 150 ℃; for 10h; under 750.075 Torr; Gas phase;

Reference yield: 99.2%

Hexafluoropropene oxide (428-59-1,25038-02-2) → 2,2,3,3,3-pentafluoropropionamide (354-76-7)

Guidance literature:

With methylamine; at 150 ℃; for 10h; under 750.075 Torr; Gas phase;

Reference yield: 83.0%

2-bromoundecafluoro-2-methyl-3-pentanone (83714-49-2) → 1,1,1,3,3,3-hexafluoroisopropyl bromide (2252-79-1) + 2,2,3,3,3-pentafluoropropionamide (354-76-7)

Guidance literature:

In diethyl ether; ammonia;

upstream raw materials:

perfluoropropionic acid methyl ester

ethyl Pentafluoropropionate

1,1,1,2,2,3,3-heptafluoro-3-isocyanato-propane

n-heptafluoropropyl fluosulfate

Downstream raw materials:

bromopentafluoroethane

2,2,3,3,3-pentafluoropropyl amine

pentafluoropropionitrile

2,2,3,3,3-pentafluoropropyl alcohol

Refernces

• 1、 Groth,R.H.. "-". . p. 102 - 105. Retrieved 1960.
• 2、 -. "Method for preparing perfluorinated nitrile through gas phase catalysis". Paragraph 0069; 0070. . Retrieved 2019/02/21.
• 3、 Krokhalev, V. M.,Saloutin, V. I.,Romas', A. D.,Ershov, B. A.,Pashkevich, K. I.. "FLUOROALKYL-CONTAINING β,β'-TRICARBONYL COMPOUNDS: TAUTOMERISM AND REACTION WITH N-NUCLEOPHILES". . p. 316 - 322. Retrieved 2007/10/02.