Technology Process of Benzoic acid,
4,4',4''-(1,9,17-trioxa-5,13,21-triazacyclotetracosane-5,13,21-triyltricarb
onyl)tris-
There total 14 articles about Benzoic acid,
4,4',4''-(1,9,17-trioxa-5,13,21-triazacyclotetracosane-5,13,21-triyltricarb
onyl)tris- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
methanol;
Yield given;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 6M hydrochlorid acid / H2O / 2 h / Heating
2: thionyl chloride / 3 h / Heating
3: 27 percent / Et3N / CH2Cl2; toluene / 24 h / Ambient temperature
4: 96 percent / borane-THF complex / tetrahydrofuran / 2 h / Heating
5: 46 percent / 1.) lithium aluminium hydride, 2.) HCl / tetrahydrofuran / 36 h / Heating
6: 87 percent / tetrahydrofuran
7: potassium hydroxide / methanol
With
hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; borane-THF; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 89 percent / pyridine / 10 deg C, 30 min, RT, 4 h
2: 95 percent / hydrochlorid acid / H2O / 2 h / Heating
3: 91 percent / sodium borohydride, borontrifluoride diethylether / tetrahydrofuran / 2 h / Ambient temperature
4: 1.) sodium hydride / 1.) THF, RT, 10 min, 2.) 4.5 h
5: 1.) lithium aluminium hydride, sulphuric acid / 1.) THF, 0 deg C, 2.) THF, RT, 3 h
6: 27 percent / Et3N / CH2Cl2; toluene / 24 h / Ambient temperature
7: 96 percent / borane-THF complex / tetrahydrofuran / 2 h / Heating
8: 46 percent / 1.) lithium aluminium hydride, 2.) HCl / tetrahydrofuran / 36 h / Heating
9: 87 percent / tetrahydrofuran
10: potassium hydroxide / methanol
With
pyridine; hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; borane-THF; sulfuric acid; boron trifluoride diethyl etherate; sodium hydride; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; toluene;