6-Phenylpiperidine-3-carboxylic acid

Base Information

Chemical Name:6-Phenylpiperidine-3-carboxylic acid
CAS No.:116140-32-0
Molecular Formula:C₁₂H₁₅NO₂
Molecular Weight:205.257
Hs Code.:
DSSTox Substance ID:DTXSID301291251
Mol file:116140-32-0.mol

Synonyms:6-phenylpiperidine-3-carboxylic acid;116140-32-0;3-Piperidinecarboxylic acid, 6-phenyl-;DTXSID301291251;6-phenylpiperidine-3-carboxylicacid;6-Phenyl-3-piperidinecarboxylic acid;6-Phenyl-piperidine-3-carboxylic acid;EN300-1477320

Suppliers and Price of 6-Phenylpiperidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-Phenylpiperidine-3-carboxylic acid

Chemical Property:

XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:224

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(NCC1C(=O)O)C2=CC=CC=C2

Technology Process of 6-Phenylpiperidine-3-carboxylic acid

There total 3 articles about 6-Phenylpiperidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 936-59-4
3-chloropropiophenone

: 116140-32-0
6-phenylpiperidine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / KOH / ethanol

2: H₂ / Raney nickel / ethanol / 6 h / 100 °C / 60800 Torr

3: H₂O / 24 h / Heating

With potassium hydroxide; hydrogen; nickel; In ethanol; water;
DOI:10.1016/0223-5234(87)90025-0

Reference yield:

: 30077-68-0
ethyl 2-cyano-5-oxo-5-phenylpentanoate

: 116140-32-0
6-phenylpiperidine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney nickel / ethanol / 6 h / 100 °C / 60800 Torr

2: H₂O / 24 h / Heating

With hydrogen; nickel; In ethanol; water;
DOI:10.1016/0223-5234(87)90025-0