CHEMBRDG-BB 4022329

Base Information

• Chemical Name: CHEMBRDG-BB 4022329
• CAS No.: 16183-32-7
• Molecular Formula: C11H16 Cl N
• Molecular Weight: 197.708
• Hs Code.: 2921499090
• Mol file: 16183-32-7.mol

Synonyms:Benzylamine,N-butyl-p-chloro- (6CI,8CI); N-(p-Chlorobenzyl)butylamine;N-Butyl-4-chlorobenzenemethanamine; N-Butyl-p-chlorobenzylamine

Chemical Property of CHEMBRDG-BB 4022329

Chemical Property:

• Vapor Pressure: 0.00984mmHg at 25°C
• Boiling Point: 264.2°Cat760mmHg
• Flash Point: 113.6°C
• PSA: 12.03000
• Density: 1.026g/cm³
• LogP: 3.62060

Purity/Quality:

98.5% ^*data from raw suppliers

BUTYL[(4-CHLOROPHENYL)METHYL]AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 4022329

There total 8 articles about CHEMBRDG-BB 4022329 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-chlorobenzaldehyde (104-88-1) + N-butylamine (109-73-9,85404-21-3) → N-(4-chlorobenzyl)butan-1-amine (16183-32-7)

Guidance literature:

With N-1-phenyl-benzotriazole-N-3-borane; In 1,2-dichloro-ethane; at 20 ℃; for 4h;

DOI:10.1039/b915361f

Reference yield: 65.0%

N-(4-chlorobenzylidene)butan-1-amine (7173-86-6) → N-(4-chlorobenzyl)butan-1-amine (16183-32-7)

Guidance literature:

With formic acid; 2F₆P^(1-)*C₄₀H₄₂ClN₄O₃Rh⁽²⁺⁾; sodium formate; silver trifluoromethanesulfonate; In methanol; at 21.84 ℃; for 16h; Reagent/catalyst; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201405129

Reference yield: 40.0%

→ N-(4-chlorobenzyl)butan-1-amine (16183-32-7)

Guidance literature:

upstream raw materials:

N-(4-chlorobenzylidene)butan-1-amine

N-butylamine

4-chlorobenzyl bromide

(E)-N-(4-chlorobenzylidene)butan-1-amine

Downstream raw materials:

C₁₂H₁₅Cl₂NO

Refernces

• 1、 Chen, Fushan,Deng, Li,Dong, Wenjin,Tang, Jie,Xian, Mo. "Rhodium catalysts with cofactor mimics for the biomimetic reduction of CN bonds". . p. 5564 - 5569. Retrieved 2021/08/25.
• 2、 McSkimming, Alex,Chan, Bun,Bhadbhade, Mohan M.,Ball, Graham E.,Colbran, Stephen B.. "Bio-inspired transition metal-organic hydride conjugates for catalysis of transfer hydrogenation: Experiment and theory". . p. 2821 - 2834. Retrieved 2015/02/05.