2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE

Base Information

• Chemical Name: 2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE
• CAS No.: 37641-48-8
• Molecular Formula: C15H12 N2 O S
• Molecular Weight: 268.339
• Hs Code.: 2933990090
• Mol file: 37641-48-8.mol

Synonyms:2,4(1H,3H)-Quinazolinedione,2-thio-3-o-tolyl- (7CI,8CI); 2-Mercapto-3-(o-methylphenyl)quinazol-4(3H)-one

Chemical Property of 2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE

Chemical Property:

• Vapor Pressure: 2.06E-07mmHg at 25°C
• Boiling Point: 424.5°Cat760mmHg
• Flash Point: 210.5°C
• PSA: 73.69000
• Density: 1.36g/cm³
• LogP: 2.98280

Purity/Quality:

99% ^*data from raw suppliers

2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE

There total 14 articles about 2-MERCAPTO-3-O-TOLYL-3H-QUINAZOLIN-4-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + o-toluidine thiocarbonate → 3-(o-methylphenyl)-2-thioquinazolin-4(3H)-one (37641-48-8)

Guidance literature:

In ethanol; for 6h; Heating;

DOI:10.1023/B:JOCC.0000047645.53340.5f

Reference yield: 88.7%

o-tolyl-dithiocarbamic acid ; compound with triethylamine (53662-44-5) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 3-(o-methylphenyl)-2-thioquinazolin-4(3H)-one (37641-48-8)

Guidance literature:

for 5h; Heating;

Reference yield: 86.0%

N-(2-methylphenyl)-methyl dithiocarbamic acid (17425-17-1) + 2-carbomethoxyaniline (134-20-3) → 3-(2-methylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline (37641-48-8)

Guidance literature:

With potassium carbonate; In ethanol; for 22h; Heating;

DOI:10.1016/j.ejmech.2007.10.001

upstream raw materials:

anthranilic acid

2-tolyl isothiocyanate

N-(2-methylphenyl)-methyl dithiocarbamic acid

2-carbomethoxyaniline

Downstream raw materials:

3-(2-methylphenyl)-2-methylsulfanyl-3H-quinazolin-4-one

C₂₄H₂₂ClN₃OS

C₂₅H₂₅N₃OS

C₂₅H₂₅N₃OS