3-Chloro-4-benzoyloxyphenylacetic acid

Base Information

Chemical Name:3-Chloro-4-benzoyloxyphenylacetic acid
CAS No.:60736-70-1
Molecular Formula:C15H13 Cl O3
Molecular Weight:276.719
Hs Code.:2918990090
European Community (EC) Number:262-396-3
DSSTox Substance ID:DTXSID20209553
Nikkaji Number:J128.641B
Wikidata:Q83083880
ChEMBL ID:CHEMBL4303431
Mol file:60736-70-1.mol

Synonyms:3-CBPAA;3-chloro-4-benzoyloxyphenylacetic acid;3-chloro-4-benzoyloxyphenylacetic acid, 3H-labeled;3-chloro-4-benzyloxyphenacetic acid;benzofac;benzofac VUFB;benzofenac;VUFB 9682;VUFB-9682

Suppliers and Price of 3-Chloro-4-benzoyloxyphenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[4-(BENZYLOXY)-3-CHLOROPHENYL]ACETIC ACID 95.00%
5MG
$ 499.42

Total 5 raw suppliers

Chemical Property of 3-Chloro-4-benzoyloxyphenylacetic acid

Chemical Property:

Vapor Pressure:1.28E-08mmHg at 25°C
Boiling Point:442.8°C at 760 mmHg
Flash Point:221.6°C
PSA：46.53000
Density:1.295g/cm³
LogP:3.54610
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:276.0553220
Heavy Atom Count:19
Complexity:289

Purity/Quality:

99% ^*data from raw suppliers

[4-(BENZYLOXY)-3-CHLOROPHENYL]ACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C=C(C=C2)CC(=O)O)Cl

Technology Process of 3-Chloro-4-benzoyloxyphenylacetic acid

There total 6 articles about 3-Chloro-4-benzoyloxyphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.2%

: 60736-70-1
3-chloro-4-benzyloxyphenylacetic acid

Guidance literature:

Reference yield:

: 63007-66-9
benzofenac methyl ester

: 60736-70-1
3-chloro-4-benzyloxyphenylacetic acid

Guidance literature:: With sodium hydroxide; pyrographite; In methanol; water;

Reference yield:

: 766-51-8
2-Chloroanisole

: 60736-70-1
3-chloro-4-benzyloxyphenylacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: HCl, As₂O₃

3: (i) aq. HBr, (ii) /BRN= 1098229/, HCl

4: (i) NaOEt, (ii) /BRN= 471308/, (iii) aq. NaOH

With hydrogenchloride; arsenic(III) trioxide;
DOI:10.1135/cccc19771723