5-(Pyridin-2-yl)-1H-indole

Base Information

Chemical Name:5-(Pyridin-2-yl)-1H-indole
CAS No.:117908-10-8
Molecular Formula:C13H10N2
Molecular Weight:194.23200
Hs Code.:
ChEMBL ID:CHEMBL4076534
DSSTox Substance ID:DTXSID30557017
Nikkaji Number:J1.781.527J
Wikidata:Q82438758
Mol file:117908-10-8.mol

Synonyms:5-(Pyridin-2-yl)-1H-indole;117908-10-8;5-pyridin-2-yl-1h-indole;5-(2-pyridyl)indole;SCHEMBL7085431;CHEMBL4076534;DTXSID30557017;AKOS006373831

Suppliers and Price of 5-(Pyridin-2-yl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-(Pyridin-2-yl)-1H-indole

Chemical Property:

Melting Point:120-124 °C
Boiling Point:409.1±20.0 °C(Predicted)
PKA:16.19±0.30(Predicted)
PSA：28.68000
Density:1.211±0.06 g/cm3(Predicted)
LogP:3.22990
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:194.084398327
Heavy Atom Count:15
Complexity:217

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C2=CC3=C(C=C2)NC=C3

Technology Process of 5-(Pyridin-2-yl)-1H-indole

There total 13 articles about 5-(Pyridin-2-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 109-04-6
2-bromo-pyridine

: 144104-59-6
1H-indole-5-boronic acid

: 117908-10-8
5-(2-pyridyl)indole

Guidance literature:: With [(t-Bu)3PH]BF₄; palladium diacetate; sodium hydroxide; at 20 ℃; for 0.25h; Inert atmosphere; Glovebox;
DOI:10.1002/ejoc.201402915

Reference yield: 91.0%

: 109-04-6
2-bromo-pyridine

: 269410-24-4
5-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

: 117908-10-8
5-(2-pyridyl)indole

Guidance literature:: With [(t-Bu)3PH]BF₄; palladium diacetate; sodium hydroxide; at 25 ℃; for 0.0833333h; Inert atmosphere; Glovebox;
DOI:10.1002/ejoc.201402915

Reference yield: 91.0%

: 109-09-1
2-chloropyridine

: 144104-59-6
1H-indole-5-boronic acid

: 117908-10-8
5-(2-pyridyl)indole

Guidance literature:: With potassium phosphate; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; tricyclohexylphosphine; In 1,4-dioxane; water; at 100 ℃; for 18h;
DOI:10.1002/anie.200503479