Ethyl N-Boc-2-piperidineacetate

Base Information

Chemical Name:Ethyl N-Boc-2-piperidineacetate
CAS No.:118667-62-2
Molecular Formula:C14H25NO4
Molecular Weight:271.357
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80555947
Mol file:118667-62-2.mol

Synonyms:118667-62-2;Ethyl N-Boc-2-piperidineacetate;tert-Butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate;1-N-BOC-2-ETHOXYCARBONYLMETHYL-PIPERIDINE;MFCD09953327;SCHEMBL12606502;DTXSID80555947;tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate;1-[(1,1-dimethylethoxy)carbonyl]-2-Piperidineacetic acid ethyl ester;AC3129;AKOS015950561;AS-77501;SY006983;CS-0452911;A893018

Suppliers and Price of Ethyl N-Boc-2-piperidineacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 95+%
5g
$ 424.00

Chemenu
tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 95%
5g
$ 400.00

Alichem
tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate
5g
$ 453.68

AK Scientific
tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate
1g
$ 262.00

Total 10 raw suppliers

Chemical Property of Ethyl N-Boc-2-piperidineacetate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:339.181oC at 760 mmHg
PKA:-2.00±0.40(Predicted)
Flash Point:158.931oC
PSA：55.84000
Density:1.049g/cm3
LogP:2.66710
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:271.17835828
Heavy Atom Count:19
Complexity:322

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CCCCN1C(=O)OC(C)(C)C

Technology Process of Ethyl N-Boc-2-piperidineacetate

There total 4 articles about Ethyl N-Boc-2-piperidineacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2739-99-3
2-ethoxycarbonylmethylpiperidine

: 24424-99-5
di-tert-butyl dicarbonate

: 118667-62-2
tert-butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Guidance literature:: In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;
DOI:10.1002/anie.201710261

Reference yield: 79.0%

: 42201-84-3
1-ethoxy-1-(tert-butyldimethylsilyloxy)ethene

: 123387-55-3,1000075-49-9,1078727-67-9
1-t-butoxycarbonyl-2-tributylstannylpiperidine

: 118667-62-2
tert-butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Guidance literature:: With ammonium cerium(IV) nitrate; In acetonitrile; at -45 ℃; for 2h;
DOI:10.1246/bcsj.66.3456

Reference yield: 48.0%

: 2739-98-2
ethyl 2-(pyridinyl-2)acetate

: 24424-99-5
di-tert-butyl dicarbonate

: 118667-62-2
tert-butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Guidance literature:: ethyl 2-(pyridinyl-2)acetate; With hydrogenchloride; platinum(IV) oxide; hydrogen; In ethanol; water; at 20 ℃; for 16h;

di-tert-butyl dicarbonate; In dichloromethane; at 0 - 20 ℃; for 16h;
DOI:10.1002/chem.202102739