Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate
CAS No.:170491-61-9
Molecular Formula:C12H21NO3
Molecular Weight:227.30000
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50440770
Nikkaji Number:J2.694.652B
Mol file:170491-61-9.mol

Synonyms:170491-61-9;Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate;1-Boc-2-(2-Oxoethyl)Piperidine;1-Piperidinecarboxylic acid, 2-(2-oxoethyl)-, 1,1-dimethylethyl ester;SCHEMBL4400837;DTXSID50440770;AMY28780;MFCD09751946;AKOS016000660;AB51441;AS-50350;FT-0741716;O12101;1-(tert-Butoxycarbonyl)piperidine 2-acetaldehyde;EN300-1721296;A904566;Tert-butyl2-(2-oxoethyl)piperidine-1-carboxylate;A1-02982;Z1505702178;TERT-BUTYL 2-(FORMYLMETHYL)PIPERIDINE-1-CARBOXYLATE

Suppliers and Price of Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate 95%
5g
$ 1446.00

Crysdot
tert-Butyl2-(2-oxoethyl)piperidine-1-carboxylate 95+%
5g
$ 831.00

Chemenu
tert-Butyl2-(2-oxoethyl)piperidine-1-carboxylate 95%
1g
$ 295.00

Biosynth Carbosynth
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate
1 g
$ 300.00

Biosynth Carbosynth
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate
500 mg
$ 200.00

Biosynth Carbosynth
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate
250 mg
$ 125.00

Biosynth Carbosynth
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate
100 mg
$ 80.00

Biosynth Carbosynth
tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate
50 mg
$ 50.00

American Custom Chemicals Corporation
TERT-BUTYL-2-(FORMYLMETHYL)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 502.25

AK Scientific
tert-Butyl2-(2-oxoethyl)piperidine-1-carboxylate
5g
$ 2002.00

Total 7 raw suppliers

Chemical Property of Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate

Chemical Property:

PSA：46.61000
LogP:2.30290
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:227.15214353
Heavy Atom Count:16
Complexity:258

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCCC1CC=O

Technology Process of Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate

There total 9 articles about Tert-butyl 2-(2-oxoethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 118811-03-3
tert-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate

: 170491-61-9
2-(2-oxoethyl)-1-piperidinecarboxylic acid tert-butyl ester

Guidance literature:: tert-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

With triethylamine; In dichloromethane; at -78 - 20 ℃; for 3h; Inert atmosphere; Schlenk technique;
DOI:10.1002/chem.202102739

Reference yield: 58.0%

: 109-92-2,25104-37-4
ethyl vinyl ether

: 195964-51-3
tert-butyl 2-methoxypiperidine-1-carboxylate

: 170491-61-9
2-(2-oxoethyl)-1-piperidinecarboxylic acid tert-butyl ester

Guidance literature:: With hydrogenchloride; sodium dodecyl-sulfate; In water; at 20 ℃;
DOI:10.1016/j.tetlet.2004.02.009

Reference yield:

: 1484-84-0
2(RS)-(2-hydroxyethyl)piperidine

: 170491-61-9
2-(2-oxoethyl)-1-piperidinecarboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / ethyl acetate

2: 89 percent / Dess-Martin periodinane

With Dess-Martin periodane; In ethyl acetate;
DOI:10.1021/ol0263144