Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate
CAS No.:118758-56-8
Molecular Formula:C13H23NO4
Molecular Weight:257.33
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10471424
Mol file:118758-56-8.mol

Synonyms:tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate;SCHEMBL1900990;DTXSID10471424;ISFYLIKYQATEJR-UHFFFAOYSA-N;MFCD16660144;AS-0775

Suppliers and Price of Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
Boc-pyrrolidin-2-yl-aceticacidethylester 96%
50mg
$ 137.00

Chemenu
tert-Butyl2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate 95%
1g
$ 380.00

Alichem
1-tert-Butyl3-ethyl2-(pyrrolidin-2-yl)malonate
1g
$ 328.00

Total 11 raw suppliers

Chemical Property of Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Chemical Property:

PSA：55.84000
LogP:2.27700
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:257.16270821
Heavy Atom Count:18
Complexity:309

Purity/Quality:

97% ^*data from raw suppliers

Boc-pyrrolidin-2-yl-aceticacidethylester 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CCCN1C(=O)OC(C)(C)C

Technology Process of Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

There total 3 articles about Tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5027-77-0
homoproline ethyl ester acetate

: 24424-99-5
di-tert-butyl dicarbonate

: 118758-56-8
tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield: 86.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 84766-91-6
tert-butyl 2-hydroxypyrrolidine-1-carboxylate

: 118758-56-8
tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

tert-butyl 2-hydroxypyrrolidine-1-carboxylate; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ol1023954