3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one

Base Information

Chemical Name:3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one
CAS No.:119704-09-5
Molecular Formula:C18H26O2SSi
Molecular Weight:334.555
Hs Code.:
DSSTox Substance ID:DTXSID20556099
Mol file:119704-09-5.mol

Synonyms:119704-09-5;DTXSID20556099;3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one

Suppliers and Price of 3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:334.14227778
Heavy Atom Count:22
Complexity:400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C(C1C2CCCCC2OC1=O)SC3=CC=CC=C3

Technology Process of 3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one

There total 7 articles about 3-[(Phenylsulfanyl)(trimethylsilyl)methyl]hexahydro-1-benzofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 79239-13-7
trimethylsilane

: 71309-69-8
[(3aS,7aR)-(3a,4,5,6,7,7a-Hexahydro-benzofuran-2-yl)oxy]-trimethyl-silane

: 119704-09-5
2-phenylthiotrimethylsilylmethyl-3,4-trans-tetramethylene-γ-butyrolactone

Guidance literature:: With zinc dibromide; In dichloromethane; at 20 ℃;
DOI:10.1016/S0040-4020(01)86667-9

Reference yield: 77.0%

: 930-69-8
sodium thiophenolate

: 105688-48-0,105688-49-1,118626-38-3,136086-83-4,136086-87-8
(3aS,7aR)-3-[1-Trimethylsilanyl-meth-(Z)-ylidene]-hexahydro-benzofuran-2-one

: 119704-09-5
2-phenylthiotrimethylsilylmethyl-3,4-trans-tetramethylene-γ-butyrolactone

Guidance literature:: In ethanol; for 16h;
DOI:10.1021/jo00043a030

Reference yield:

: 142636-23-5
(1R*,2S*)-2-(trimethylsilanylethynyl)cyclohexanol

: 119704-09-5
2-phenylthiotrimethylsilylmethyl-3,4-trans-tetramethylene-γ-butyrolactone

Guidance literature:: Multi-step reaction with 4 steps

1: N(Et)3 / benzene / Ambient temperature

2: 66 percent / pyridine / benzene / 1 h

3: 78 percent / n-Bu₃SnH, AIBN / benzene / Heating

4: 77 percent / ethanol / 16 h

With pyridine; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; triethylamine; In ethanol; benzene;
DOI:10.1021/jo00043a030