Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate

Base Information

Chemical Name:Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate
CAS No.:121017-79-6
Molecular Formula:C15H12N2O3
Molecular Weight:268.272
Hs Code.:
DSSTox Substance ID:DTXSID801151727
Nikkaji Number:J563.156D
Mol file:121017-79-6.mol

Synonyms:DTXSID801151727;Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate;121017-79-6

Suppliers and Price of Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:268.08479225
Heavy Atom Count:20
Complexity:531

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(NC(=O)C(=C1)C#N)CC2=CC=CC=C2

Technology Process of Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate

There total 1 articles about Methyl 5-cyano-1,6-dihydro-6-oxo-2-(phenylmethyl)-3-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 116344-11-7
methyl 2-((dimethylamino)methylene)-3-oxo-4-phenylbutanoate

: 107-91-5
cyanoacetic acid amide

: 121017-79-6
2-benzyl-5-cyano-1,6-dihydro-6-oxo-3-methoxycarbonyl pyridine

Guidance literature:: With sodium ethanolate; In ethanol; for 24h; Ambient temperature;
DOI:10.1016/0223-5234(89)90057-3

Reference yield: 98.0%

: 121017-79-6
2-benzyl-5-cyano-1,6-dihydro-6-oxo-3-methoxycarbonyl pyridine

: 121017-85-4
2-Benzyl-5-cyano-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 8h; Heating;
DOI:10.1016/0223-5234(89)90057-3

Reference yield:

: 121017-79-6
2-benzyl-5-cyano-1,6-dihydro-6-oxo-3-methoxycarbonyl pyridine

: 56304-64-4
6-benzyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / KOH / aq. ethanol / 8 h / Heating

2: 70 percent / copper powder / quinoline / 3 h / Heating

With potassium hydroxide; copper; In quinoline; ethanol;
DOI:10.1016/0223-5234(89)90057-3