Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester, (R)-

Base Information

• Chemical Name: Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester, (R)-
• CAS No.: 121170-46-5
• Molecular Formula: C22H25F3O3
• Molecular Weight: 394.434
• Mol file: 121170-46-5.mol

Synonyms:

Chemical Property of Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester, (R)-

There total 3 articles about Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Ethyl 4-bromobenzoate (5798-75-4) + (2R)-1,1,1-trifluorooctan-2-ol (121170-45-4) → (R)-(+)-4-benzyloxybenzoic acid 1-trifluoromethylheptyl ester (121170-46-5)

Guidance literature:

With pyridine; In thionyl chloride; N,N-dimethyl-formamide;

Reference yield:

4-(benzyloxy)benzoic acid chloride (1486-50-6) + sodium carbonate (497-19-8) + (2R)-1,1,1-trifluorooctan-2-ol (121170-45-4) → (R)-(+)-4-benzyloxybenzoic acid 1-trifluoromethylheptyl ester (121170-46-5)

Guidance literature:

With 2-(Dimethylamino)pyridine; triethylamine; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane;

Reference yield:

4-(benzyloxy)benzoic acid chloride (1486-50-6) + (2R)-1,1,1-trifluorooctan-2-ol (121170-45-4) → (R)-(+)-4-benzyloxybenzoic acid 1-trifluoromethylheptyl ester (121170-46-5)

Guidance literature:

With TEA; In dichloromethane;

upstream raw materials:

4-(benzyloxy)benzoic acid chloride

(2R)-1,1,1-trifluorooctan-2-ol

Ethyl 4-bromobenzoate

sodium carbonate

Downstream raw materials:

(R)-(+)-4-hydroxybenzoic acid 1-trifluoromethylheptyl ester

Refernces

• 1、 Suzuki,Koide,Aihara,Kawamura,Suenaga,Kitazume. "Effect of molecular polarity and conjugated system on antiferroelectricity in AFLC's". . p. 351 - 360. Retrieved 2007/10/03.