2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-

Base Information

Chemical Name:2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-
CAS No.:121217-55-8
Molecular Formula:C₁₆H₁₇N₃O₃
Molecular Weight:299.329
Hs Code.:
DSSTox Substance ID:DTXSID70391437
Mol file:121217-55-8.mol

Synonyms:2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-;121217-55-8;DTXSID70391437

Suppliers and Price of 2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:299.12699141
Heavy Atom Count:22
Complexity:495

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)C(=CC2=CC=CC=C2[N+](=O)[O-])C#N

Technology Process of 2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)-

There total 3 articles about 2-Propenamide, 2-cyano-N-cyclohexyl-3-(2-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 15029-38-6
2-cyano-N-cyclohexylacetamide

: 552-89-6
2-nitro-benzaldehyde

: 121217-55-8
(Z)-2-Cyano-N-cyclohexyl-3-(2-nitro-phenyl)-acrylamide

Guidance literature:: With piperidine; In ethanol; for 1h; Heating;
DOI:10.1007/BF00633505

Reference yield: 33.0%

: 20374-51-0
2-cyano-3-(2'-nitro-1'-phenyl)acrylic acid

: 108-91-8,157973-60-9
cyclohexylamine

: 121217-55-8
(Z)-2-Cyano-N-cyclohexyl-3-(2-nitro-phenyl)-acrylamide

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 0 - 20 ℃; for 6.5h;

Reference yield:

: 552-89-6
2-nitro-benzaldehyde

: 121217-55-8
(Z)-2-Cyano-N-cyclohexyl-3-(2-nitro-phenyl)-acrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / piperidine, pyridine / benzene / 10 h / Heating

2: 33 percent / triethylamine, POCl₃ / CH₂Cl₂ / 6.5 h / 0 - 20 °C

With piperidine; pyridine; triethylamine; trichlorophosphate; In dichloromethane; benzene;